160061-53-0

Basic information

• Product Name: 2-Oxo-butyric acid (R)-2-tert-butoxycarbonylamino-2-phenyl-ethyl ester
• CAS NO: 160061-53-0
• Molecular Weight: 321.373
• Mol File: 160061-53-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Oxo-butyric acid (R)-2-tert-butoxycarbonylamino-2-phenyl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxo-butyric acid (R)-2-tert-butoxycarbonylamino-2-phenyl-ethyl ester(160061-53-0)
• EPA Substance Registry System: 2-Oxo-butyric acid (R)-2-tert-butoxycarbonylamino-2-phenyl-ethyl ester(160061-53-0)

Safety Data

• Hazardous Substances Data: 160061-53-0(Hazardous Substances Data)

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 600-18-0 2-Oxobutyric acid 
• 67341-01-9 (R)-N-(tert-butoxycarbonyl)phenylglycinol 

Downstream Products

• 160061-54-1 (5R)-3-ethyl-5-phenyl-3,5-dehydromorpholin-2-one 
• 160061-55-2 (3S,5R)-3-ethyl-5-phenylmorpholin-2-one 

Relevant articles and documents

Synthesis of homochiral α-amino acids by reductive amination of α-ketoacids via 3-substituted-5-phenyl-3,4-dehydromorpholin-2-ones: Synthesis of (S)- and (R)-2-aminobutanoic acid

2-Oxobutanoic acid has been converted to (R)- or (S)-2-aminobutanoic acid via highly diastereocontrolled hydrogenation of the corresponding homochiral 3-ethyl-5-phenyl-3,4-dehydromorpholin-2-one derivatives.