160135-02-4

Basic information

• Product Name: [(3S,7R)-3-((S)-2-Acetylsulfanyl-3-phenyl-propionylamino)-7-cyclopropylmethyl-2-oxo-azepan-1-yl]-acetic acid methyl ester
• CAS NO: 160135-02-4
• Molecular Weight: 460.594
• Mol File: 160135-02-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(3S,7R)-3-((S)-2-Acetylsulfanyl-3-phenyl-propionylamino)-7-cyclopropylmethyl-2-oxo-azepan-1-yl]-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(3S,7R)-3-((S)-2-Acetylsulfanyl-3-phenyl-propionylamino)-7-cyclopropylmethyl-2-oxo-azepan-1-yl]-acetic acid methyl ester(160135-02-4)
• EPA Substance Registry System: [(3S,7R)-3-((S)-2-Acetylsulfanyl-3-phenyl-propionylamino)-7-cyclopropylmethyl-2-oxo-azepan-1-yl]-acetic acid methyl ester(160135-02-4)

Safety Data

• Hazardous Substances Data: 160135-02-4(Hazardous Substances Data)

Upstream product

• 160135-01-3 (3S)-trans-7-(cyclopropylmethyl)-3-(2,3-dihydro-1,3-dioxo-1H-isoindol-2-yl)hexahydro-2-oxo-1H-azepine-1-acetic acid methyl ester 
• 155013-05-1 (3S)-trans-hexahydro-2-oxo-3-phthalimido-7-(2-propenyl)-1H-azepine-1-acetic acid methyl ester 
• 76932-17-7 (S)-2-acetylthio-3-phenylpropanoic acid 
• 171900-68-8 (3S)-trans-3-amino-7-(cyclopropylmethyl)hexahydro-2-oxo-1H-azepine-1-acetic acid methyl ester 

Relevant articles and documents

Dual metalloprotease inhibitors. 6. Incorporation of bicyclic and substituted monocyclic azepinones as dipeptide surrogates in angiotensin-converting enzyme/neutral endopeptidase inhibitors.

A series of substituted monocyclic and bicyclic azepinones were incorporated as dipeptide surrogates in mercaptoacetyl dipeptides with the desire to generate a single compound which would potently inhibit both angiotensin-converting enzyme (ACE) and neutr