160153-70-8Relevant articles and documents
Novel indole-2-carboxamide and cycloalkeno[1,2-b]indole derivatives. Structure-activity relationships for high inhibition of human LDL peroxidation
Kuehm-Caubere, Catherine,Caubere, Paul,Jamart-Gregoire, Brigitte,Negre-Salvayre, Anne,Bonnefont-Rousselot, Dominique,Bizot-Espiard, Jean-Guy,Pfeiffer, Bruno,Caignard, Daniel-Henri,Guardiola-Lemaitre, Béatrice,Renard, Pierre
, p. 1201 - 1210 (1997)
Series of indole-2-carboxamide and cycloalkeno[1,2-b]indole derivatives were synthesized and evaluated in order to determine the necessary structural requirements for a high inhibition of human LDL copper-induced peroxidation. Various modulations were sys
Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase
Mahboobi, Siavosh,Teller, Steffen,Pongratz, Herwig,Hufsky, Harald,Sellmer, Andreas,Botzki, Alexander,Uecker, Andrea,Beckers, Thomas,Baasner, Silke,Sch?chtele, Christoph,überall, Florian,Kassack, Matthias U.,Dove, Stefan,B?hmer, Frank-D.
, p. 1002 - 1018 (2007/10/03)
The novel lead bis(1H-2-indolyl)methanone inhibits autophosphorylation of platelet-derived growth factor (PDGF) receptor tyrosine kinase in intact cells. Various substituents in the 5- or 6-position of one indole ring increase or preserve potency, whereas
