160237-09-2

Basic information

• Product Name: C₄₈H₅₄NO₁₈P
• Synonyms: C₄₈H₅₄NO₁₈P
• CAS NO: 160237-09-2
• Molecular Weight: 963.926
• Mol File: 160237-09-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₈H₅₄NO₁₈P(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₈H₅₄NO₁₈P(160237-09-2)
• EPA Substance Registry System: C₄₈H₅₄NO₁₈P(160237-09-2)

Safety Data

• Hazardous Substances Data: 160237-09-2(Hazardous Substances Data)

Upstream product

• 160237-33-2 C₆₂H₆₆NO₁₈P 
• 160237-31-0 C₅₅H₆₉NO₁₄SSi 
• 160237-25-2 BMS-184476 
• 160237-26-3 C₆₂H₆₆NO₁₈P 

Downstream Products

• 33069-62-4 taxol 
• 148930-30-7 2’-carboxybenzoylpaclitaxel 
• 160237-27-4 C₅₇H₆₁NO₁₆S 

Relevant articles and documents

Synthesis and antitumor evaluation of paclitaxel phosphonooxymethyl ethers: A novel class of water soluble paclitaxel pro-drugs

The synthesis, pharmacokinetic properties, and antitumor evaluation of novel paclitaxel phosphonooxymethyl ether derivatives 8-11 and salts thereof is described. These compounds exhibit improved water solubility as compared to paclitaxel (1) and upon incubation with plasma and alkaline phosphatase they readily release parent drug. The in vivo antitumor evaluation of compounds 8-11 established them as suitable pro-drugs of paclitaxel.