1602485-05-1Relevant articles and documents
Copper-catalyzed intermolecular trifluoromethylazidation of alkenes: Convenient access to CF3-containing alkyl azides
Wang, Fei,Qi, Xiaoxu,Liang, Zhaoli,Chen, Pinhong,Liu, Guosheng
supporting information, p. 1881 - 1886 (2014/03/21)
A novel copper-catalyzed intermolecular trifluoromethylazidation of alkenes has been developed under mild reaction conditions. A variety of CF 3-containing organoazides were directly synthesized from a wide range of olefins, including activated and unactivated alkenes, and the resulting products can be easily transformed into the corresponding CF3- containing amine derivatives. The title reaction proceeds with a CF 3+ reagent under mild reaction conditions. This transformation presents a broad substrate scope and good functional-group tolerance. A variety of CF3-containing organoazides are directly synthesized from a wide range of olefins, including activated and unactivated alkenes. The resulting products are easily transformed into the corresponding amine derivatives. Copyright
