1603105-46-9Relevant articles and documents
Novel ultra-small Pd NPs on SOS spheres: A new catalyst for domino intramolecular Heck and intermolecular Sonogashira couplings
Lakshminarayana, Bhairi,Vinodkumar,Satyanarayana,Subrahmanyam
, p. 4568 - 4578 (2020)
We report a novel catalyst Pd/SOS that catalyzes the dual C-C bond forming coupling of an iodoarene moiety with an internal alkene and an external alkyne via an intramolecular Heck reaction, followed by an intermolecular Sonogashira reaction, respectively
Domino [Pd]-Catalysis: Heck followed by decarboxylative Sonogashira couplings under microwave irradiation in aqueous medium
Ramesh, Karu,Satyanarayana, Gedu
, p. 58 - 71 (2019/04/25)
A copper free [Pd]-catalyzed domino intramolecular Heck and intermolecular decarboxylative Sonogashira couplings, for the synthesis of alkyne bearing heterocyclic compounds with a quaternary carbon atom, is described. Notably, this dual bond forming strategy is successful in water solvent, under microwave irradiation. This one-pot operation enabled the formation of a variety of dihydrobenzofurans, indolines and oxindoles, in very good to near quantitative yields. Notably, unlike earlier reports, the present strategy is successful in delivering the products with short alkyl substituents on acetylene carbon, which is first of its kind.
Microwave-Assisted Domino Palladium Catalysis in Water: A Diverse Synthesis of 3,3′-Disubstituted Heterocyclic Compounds
Ramesh, Karu,Basuli, Suchand,Satyanarayana, Gedu
, p. 2171 - 2177 (2018/05/14)
An environmentally benign microwave-assisted domino [Pd]-catalyzed reaction, for the efficient and diverse synthesis of 3,3′-disubstituted indolines, oxindoles, and dihydrobenzofurans, is presented. Significantly, water served as the sole green solvent and the strategy displayed an excellent functional-group tolerance. Remarkably, the process was also amenable to unmasked functional groups and furnished the products, in very good to almost quantitative yields.
