1603163-34-3Relevant articles and documents
Catalyst-free concise synthesis of imidazo[1,2-a]pyrrolo[3,4-e]pyridine derivatives
Chen, Xuebing,Zhu, Li,Fang, Li,Yan, Shengjiao,Lin, Jun
, p. 9926 - 9934 (2014/03/21)
An eco-benign and highly efficient aza-ene reaction for preparing imidazo[1,2-a]pyrrolo[3,4-e]pyridine derivatives from heterocyclic ketene aminals (HKAs) and 2,3-dioxopyrrolidines has been developed in environmentally benign solvent systems, as well as in the absence of any catalyst. The procedures feature excellent yields, short reaction times, a convenient one-pot method, and simple purification that not only minimise the generation of waste but also simplify the work-up procedure.