160333-50-6

Basic information

• Product Name: 1-({[(3R)-tetrahydrofuran-3-yloxy]carbonyl}oxy)pyrrolidine-2,5-dione
• Synonyms: 1-({[(3R)-tetrahydrofuran-3-yloxy]carbonyl}oxy)pyrrolidine-2,5-dione
• CAS NO: 160333-50-6
• Molecular Weight: 229.189
• Mol File: 160333-50-6.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: 1-({[(3R)-tetrahydrofuran-3-yloxy]carbonyl}oxy)pyrrolidine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-({[(3R)-tetrahydrofuran-3-yloxy]carbonyl}oxy)pyrrolidine-2,5-dione(160333-50-6)
• EPA Substance Registry System: 1-({[(3R)-tetrahydrofuran-3-yloxy]carbonyl}oxy)pyrrolidine-2,5-dione(160333-50-6)

Safety Data

• Hazardous Substances Data: 160333-50-6(Hazardous Substances Data)

Usage

Description

1-([(3R)-tetrahydrofuran-3-yloxy]carbonyloxy)pyrrolidine-2,5-dione, also known as rapamycin, is a macrolide compound that possesses both immunosuppressant and anti-cancer properties. It is characterized by its ability to inhibit the activation of T-lymphocytes and the production of interleukin-2, which are essential components of the immune response. Rapamycin has also demonstrated potential in treating certain types of cancer and has been studied for its possible anti-aging effects, as it has been shown to extend the lifespan of certain organisms.

Uses

Used in Immunosuppressive Applications:
Rapamycin is utilized as an immunosuppressant, primarily to prevent organ rejection in transplant patients. By inhibiting the activation of T-lymphocytes and the production of interleukin-2, it effectively manages the immune response and reduces the risk of graft rejection.
Used in Cancer Treatment:
Rapamycin is employed in the treatment of certain types of cancer due to its ability to inhibit the growth and proliferation of cancer cells. It has shown promise in targeting various cancer-related pathways, making it a potential therapeutic option for patients with specific malignancies.
Used in Anti-Aging Research:
Rapamycin has been studied for its potential anti-aging effects, as it has been demonstrated to extend the lifespan of certain organisms. This property has led to investigations into its use in anti-aging therapies and interventions aimed at promoting longevity and overall health.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, rapamycin is used as an active ingredient in the development of drugs for immunosuppression and cancer treatment. Its unique properties make it a valuable compound for creating novel therapeutics that can address a range of medical conditions.
Used in Research and Development:
Rapamycin is also used in research and development settings to study its mechanisms of action and potential applications in various fields, including immunology, oncology, and gerontology. This research can lead to the discovery of new therapeutic targets and the development of innovative treatments for a variety of diseases and conditions.

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