160334-75-8

Basic information

• Product Name: C₄₉H₅₇NO₂₂P₂
• Synonyms: C₄₉H₅₇NO₂₂P₂
• CAS NO: 160334-75-8
• Molecular Weight: 1073.93
• Mol File: 160334-75-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₉H₅₇NO₂₂P₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₉H₅₇NO₂₂P₂(160334-75-8)
• EPA Substance Registry System: C₄₉H₅₇NO₂₂P₂(160334-75-8)

Safety Data

• Hazardous Substances Data: 160334-75-8(Hazardous Substances Data)

Downstream Products

• 160237-27-4 C₅₇H₆₁NO₁₆S 
• 160237-34-3 C₅₁H₅₉NO₁₄S₂ 
• 148930-30-7 2’-carboxybenzoylpaclitaxel 
• 33069-62-4 taxol 

Relevant articles and documents

Synthesis and antitumor evaluation of paclitaxel phosphonooxymethyl ethers: A novel class of water soluble paclitaxel pro-drugs

The synthesis, pharmacokinetic properties, and antitumor evaluation of novel paclitaxel phosphonooxymethyl ether derivatives 8-11 and salts thereof is described. These compounds exhibit improved water solubility as compared to paclitaxel (1) and upon incubation with plasma and alkaline phosphatase they readily release parent drug. The in vivo antitumor evaluation of compounds 8-11 established them as suitable pro-drugs of paclitaxel.