1605-49-8Relevant articles and documents
Palladium-catalyzed microwave-assisted amination of 1-bromonaphthalenes and 5-and 8-bromoquinolines
Wang, Tammy,Magnin, David R.,Hamann, Lawrence G.
, p. 897 - 900 (2003)
1-Aminonaphthalenes and 5-and 8-aminoquinolines were rapidly prepared from the respective aryl bromides in good yields by Pd-catalyzed aryl amination under microwave conditions. Consistent improvements in yields over those obtained under standard conditions were seen with quinoline substrates. In the cases where 5-bromo-8-cyanoquinoline was used as a substrate, no desired products were obtained under standard conditions with a number of different primary and secondary amines. However, microwave conditions provided the desired products in good to excellent yields.
