160711-96-6Relevant articles and documents
Novel Solid Supports for the Preparation of 3'-Derivatized Oligonucleotides: Introduction of 3'-Alkylphosphate Tether Groups Bearing Amino, Carboxy, Carboxamido, and Mercapto Functionalities
Hovinen, Jari,Guzaev, Andrei,Azhayev, Alex,Loennberg, Harri
, p. 7203 - 7218 (1994)
Syntheses of 5 non-nucleosidic solid supports (1-5) that enable preparation of oligonucleotides bearing a carboxy,- amino,- carboxamido,- or mercaptoalkyl spacer arm at their 3'-terminus are described.They all contain an ester bond of moderate susceptibil