1608108-44-6

Basic information

• Product Name: (E)-1-(1H-pyrrol-1-yl)-3-(m-tolyl)prop-2-en-1-one
• Synonyms: (E)-1-(1H-pyrrol-1-yl)-3-(m-tolyl)prop-2-en-1-one
• CAS NO: 1608108-44-6
• Molecular Weight: 211.263
• Mol File: 1608108-44-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(1H-pyrrol-1-yl)-3-(m-tolyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(1H-pyrrol-1-yl)-3-(m-tolyl)prop-2-en-1-one(1608108-44-6)
• EPA Substance Registry System: (E)-1-(1H-pyrrol-1-yl)-3-(m-tolyl)prop-2-en-1-one(1608108-44-6)

Safety Data

• Hazardous Substances Data: 1608108-44-6(Hazardous Substances Data)

Upstream product

• 1346683-43-9 dimethyl (2-oxo-2-(1H-pyrrol-1-yl)ethyl)phosphonate 
• 620-23-5 m-tolyl aldehyde 

Downstream Products

• 1608108-60-6 ((1S,2S,3R)-4-methylene-2-(m-tolyl)-3-((trimethylsilyl)ethynyl)cyclopentyl)(1H-pyrrol-1-yl)methanone 

Relevant articles and documents

An approach for rapid increase in molecular complexity: Atom economic routes to fused polycyclic ring systems

A protocol for the asymmetric trimethylenemethane (TMM) [3 + 2] cycloaddition reaction of alkynyl-substituted TMM donors and unsaturated N-acyl pyrroles employing a chiral bisdiamidophosphite ligand has been developed. This process generates alkynyl-substituted cyclopentanes in high yields and diastereo- and enantioselectivities. These chiral precursors are employed for the atom economic assembly of fused polycyclic hydrocarbons with hydroindene, hydroazulene, and hydrocyclopentanaphthalene scaffolds by consecutive cycloaddition reactions.