1608127-09-8

Basic information

• Product Name: C₂₂H₃₃N₅O₆
• Synonyms: C₂₂H₃₃N₅O₆
• CAS NO: 1608127-09-8
• Molecular Weight: 463.534
• Mol File: 1608127-09-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₃₃N₅O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₃₃N₅O₆(1608127-09-8)
• EPA Substance Registry System: C₂₂H₃₃N₅O₆(1608127-09-8)

Safety Data

• Hazardous Substances Data: 1608127-09-8(Hazardous Substances Data)

Upstream product

• 1037794-22-1 (S)-2-amino-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide 
• 1343476-61-8 (S)-2,5-dioxopyrrolidin-1-yl 2-(((allyloxy)carbonyl)amino)-3- methylbutanoate 
• 870487-04-0 (S)-(9H-fluoren-9-yl)methyl (1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)carbamate 
• 133174-15-9 (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-ureidopentanoic acid 
• 623-04-1 4-aminobenzenemethanol 

Downstream Products

• 1608127-10-1 C₅₀H₆₀N₆O₁₈ 
• 1022094-34-3 C₄₆H₅₆N₆O₁₆ 

Relevant articles and documents

MODIFIED ANTIBODY, ANTIBODY-CONJUGATE AND PROCESS FOR THE PREPARATION THEREOF

The present invention relates to an antibody comprising a GlcNAc-S(A)x substituent, wherein S(A)x is a sugar derivative comprising x functional groups A wherein A is independently selected from the group consisting of an azido group, a keto group and an alkynyl group and x is 1, 2, 3 or 4, wherein said GlcNAc-S(A)x substituent is bonded to the antibody via CI of the N-acetylglucosamine of said GlcNAc-S(A)x substituent, and wherein said N-acetylglucosamine is optionally fucosylated. The invention also relates to an antibody-conjugate, in particular to an antibody- conjugate according to the Formula (20) or (20b), wherein AB is an antibody, S is a sugar or a sugar derivative, D is a molecule of interest, and wherein said N- acetylglucosamine is optionally fucosylated (b is 0 or 1). The invention further relates to a process for the preparation of a modified antibody, to a process for the preparation of an antibody-conjugate, and to said antibody-conjugate for use as a medicament. In addition, the invention relates to a kit of parts comprising an azide-modified antibody and a linker-conjugate, wherein said linker-conjugate comprises a (hetero)cycloalkynyl group and one or more molecules of interest.