1609574-73-3

Basic information

• Product Name: N-(1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-3,4,5-trimethoxybenzamide
• Synonyms: N-(1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-3,4,5-trimethoxybenzamide
• CAS NO: 1609574-73-3
• Molecular Weight: 457.388
• Mol File: 1609574-73-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-3,4,5-trimethoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-3,4,5-trimethoxybenzamide(1609574-73-3)
• EPA Substance Registry System: N-(1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-3,4,5-trimethoxybenzamide(1609574-73-3)

Safety Data

• Hazardous Substances Data: 1609574-73-3(Hazardous Substances Data)

Upstream product

• 1254062-21-9 4-amino-1-((6aR,8R,9aR)-9,9-difluoro-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f] [1,3,5,2,4]trioxadisilocin-8-yl)pyrimidin-2(1H)-one 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 95058-81-4 gemcitabine 
• 1609574-86-8 C₃₁H₄₇F₂N₃O₉Si₂ 

Relevant articles and documents

Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma

Many successful anti-viral and anti-cancer drugs are nucleoside analogs, which disrupt RNA and/or DNA synthesis. Here, we present liver-specific prodrugs of the chemotherapy drug gemcitabine (2′,2′-difluorodeoxycytidine) for the treatment of hepatitis C v