1609985-46-7Relevant articles and documents
Nickel-catalyzed oxidative cyclotrimerization of α-amino ketones: Selective synthesis of pyrazoles
Tang, Ri-Yuan,Guo, Xiao-Kang,Hu, Ming,Wang, Zhi-Qiang,Xiang, Jian-Nan,Li, Jin-Heng
supporting information, p. 64 - 68 (2014/01/06)
A new strategy for the synthesis of 3-methylene-2,3-dihydro-1H-pyrazoles is presented by Ni-catalyzed oxidative cyclotrimerization of α-amino ketones. This unprecedented method allows three α-amino ketones to undergo sequential multiple deprotonations and deamination through two C-C bonds and one N-N bond formation cascade. Georg Thieme Verlag Stuttgart · New York.