1609986-27-7

Basic information

• Product Name: C₁₅H₁₄N₂O₆
• Synonyms: C₁₅H₁₄N₂O₆
• CAS NO: 1609986-27-7
• Molecular Weight: 318.286
• Mol File: 1609986-27-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₄N₂O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₄N₂O₆(1609986-27-7)
• EPA Substance Registry System: C₁₅H₁₄N₂O₆(1609986-27-7)

Safety Data

• Hazardous Substances Data: 1609986-27-7(Hazardous Substances Data)

Upstream product

• 1849-54-3 3-hydroxypyridine-4-carboxaldehyde 
• 53413-67-5 6-nitroveratrylbromide 

Downstream Products

• 1609986-39-1 C₂₆H₂₀F₃N₃O₉ 
• 1609986-32-4 (3-((4,5-dimethoxy-2-nitrobenzyl)oxy)pyridin-4-yl)methanol 

Relevant articles and documents

Disassembly kinetics of quinone-methide-based self-immolative spacers that contain aromatic nitrogen heterocycles

We prepared several pyridine- and pyrimidine-based self-immolative spacer groups to evaluate the significance of the resonance energy of the spacer aromatic ring on the kinetics of 1,4- and 1,6-elimination reactions, which govern spacer disassembly. Subsequently, we relied on a photoactivation procedure to accurately analyze the disassembly kinetics. Beyond providing new results that are relevant for deriving quantitative structure-property relationships, herein, we demonstrate that pH value can be used as an efficient parameter to finely control the disassembly time of a self-immolative spacer after an initial activation. Burn rubber: Kinetic analysis of the pH-dependent disassembly of self-immolative spacers that contain aromatic nitrogen heterocycles was performed. Electron-poor pyrimidine cores exhibited the longest disassembly times. This study confirms the trend that electron-rich aryl cores accelerate self-immolation.