16105-78-5 Usage
Description
(±)-N-ethyl-alpha-methylphenethylamine hydrochloride, also known as N-Ethylamphetamine (EMA), is an N-substituted amphetamine with an ethyl group on the amphetamine backbone. It belongs to the phenethylamine and amphetamine chemical classes and is recognized as a stimulant drug. EMA has been marketed under the tradename Apetinil and has been subject to abuse as a "designer drug" alternative to amphetamine and potentially methamphetamine. (±)-N-ethyl-alpha-methylphenethylamine hydrochloride is primarily intended for forensic or research applications.
Uses
Used in Pharmaceutical Industry:
(±)-N-ethyl-alpha-methylphenethylamine hydrochloride is used as an anorectic agent for its stimulant properties, which help in suppressing appetite and promoting weight loss. It was marketed under the tradename Apetinil for this purpose.
Used in Forensic Applications:
In the forensic field, (±)-N-ethyl-alpha-methylphenethylamine hydrochloride is utilized for the detection and analysis of its presence in cases related to drug abuse or as a "designer drug" alternative to amphetamine and methamphetamine.
Used in Research Applications:
(±)-N-ethyl-alpha-methylphenethylamine hydrochloride serves as a valuable compound in research settings, where it can be studied for its effects on the central nervous system, its potential for abuse, and its interactions with other substances. This research can contribute to the development of new drugs, understanding of addiction, and the improvement of drug testing methods.
Check Digit Verification of cas no
The CAS Registry Mumber 16105-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,0 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16105-78:
(7*1)+(6*6)+(5*1)+(4*0)+(3*5)+(2*7)+(1*8)=85
85 % 10 = 5
So 16105-78-5 is a valid CAS Registry Number.
16105-78-5Relevant articles and documents
Involvement of CYP2D6 in the in vitro metabolism of amphetamine, two N-alkylamphetamines and their 4-methoxylated derivatives
Bach, Mimi V.,Coutts,Baker
, p. 719 - 732 (2007/10/03)
1. Amphetamine (AM) and five amphetamine derivatives, N-ethylamphetamine (NEA), N-butylamphetamine (NBA), 4-methoxyamphetamine (M-AM), 4-methoxy-N-ethylamphetamine (M-NEA) and 4-methoxy-N-butylamphetamine (M-NBA) were incubated with microsomal preparations from cells expressing human CYP2D6 to determine whether the enzyme was capable of catalyzing the direct ring oxidation of all substrates; the N-dealkylation of NEA, NBA, M-NEA and M-NBA; and the O-demethylation of M-AM, M-NEA and M-NBA. 2. None of the six compounds examined was N-dealkylated to any extent. 3. The only metabolites produced from AM, NEA and NBA were the corresponding ring 4-hydroxylated compounds, and the rates of formation were low. 4. All ring 4-methoxylated substrates were efficiently O-demethylated by CYP2D6 to their corresponding phenols. The size of the N-alkyl group influenced the rates of formation of these phenolamines. In contrast to reported findings with 2- and 3-methoxyamphetamines, none of the 4-methoxyamphetamines was ring-oxidized in the CYP2D6 enzyme system to 2- or 3-hydroxy-4-methoxyamphetamines or to dihydroxy-amphetamines.
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.