161086-52-8Relevant articles and documents
Synthesis of symmetrical pseudopeptides as potential inhibitors of the human immunodeficiency virus-1 protease
Langlois,Quintard,Abalain
, p. 639 - 647 (2007/10/02)
It is demonstrated that HIV-1 protease is essential for the assembly and infectivity of the acquired immunodeficiency syndrome (AIDS) virus. This protease is an aspartyl protease with a 2-fold symmetry axis. Potential inhibitors were synthesized and consi