161144-25-8

Basic information

• Product Name: 3-Ethoxy-1-phenyl-but-3-en-2-one
• Synonyms: 3-Ethoxy-1-phenyl-but-3-en-2-one
• CAS NO: 161144-25-8
• Molecular Weight: 190.242
• Mol File: 161144-25-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Ethoxy-1-phenyl-but-3-en-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethoxy-1-phenyl-but-3-en-2-one(161144-25-8)
• EPA Substance Registry System: 3-Ethoxy-1-phenyl-but-3-en-2-one(161144-25-8)

Safety Data

• Hazardous Substances Data: 161144-25-8(Hazardous Substances Data)

Upstream product

• 95092-10-7 N-methoxy-N-methyl-2-phenylacetamide 
• 109-92-2 ethyl vinyl ether 
• 18925-69-4 N,N-dimethyl-2-phenylacetamide 
• 103-82-2 phenylacetic acid 

Downstream Products

• 749888-22-0 3-ethoxy-1-phenyl-2-trimethylsilanylmethyl-but-3-en-2-ol 

Relevant articles and documents

An efficient synthesis of α-branched enones

A new method for preparing α-branched enones from carboxylic acid derivatives is reported. The procedure commenced by the reaction of N,O-dimethylamides with a masked acyl anion equivalent, followed by the addition of (trimethylsilyl-methyl)cerium dichloride to give intermediates that undergo Lewis acid mediated olefination to produce enol ethers that are then hydrolyzed to afford simple α-branched enones in high overall yields.