161154-73-0Relevant articles and documents
Spiroannelation Starting from β-Trifluoroacetylpyrrolidone
Bouillon, J.-Ph.,Janousek, Z.,Viehe, H.G.
, p. 2315 - 2322 (2007/10/02)
β-Trifluoroacetyl-N-methyl-2-pyrrolidone undergoes once or twice the Robinson annelation with methylvinylketone.The spiro compound 6 can be trifluoroacetylated to the corresponding 1,3-diketone 8 for heterocyclizations with bis-nucleophiles.Furthermore, 6 furnishes spirocyclohexadienone 15 with potential for aromatisation. 3-Trifluoroacetyl-2-pyrrolidone, the Robinson annelation, spirocyclic compounds, selenoxide elimination, cyclohexadienone