16119-56-5

Basic information

• Product Name: 5'H-Pregna-1,4,9(11)-trieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-2'-methyl-, (16b)- (9CI)
• Synonyms: 5'bH-Pregna-1,4,9(11)-trieno[17,16-d]oxazole-3,20-dione,21-hydroxy-2'-methyl-, acetate (ester) (8CI);2H-Naphth[2',1':4,5]indeno[1,2-d]oxazole,5'H-pregna-1,4,9(11)-trieno[17,16-d]oxazole deriv.;21-Hydroxy-3-oxo-1,4,9(11)-pregnatrieno[17a,16a-d]-2'-methyloxazoline acetate
• CAS NO: 16119-56-5
• Molecular Formula: C25H29 N O5
• Molecular Weight: 423.509
• Mol File: 16119-56-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 573.3°Cat760mmHg
• Flash Point: 216.2°C
• Density: 1.34g/cm³
• CAS DataBase Reference: 5'H-Pregna-1,4,9(11)-trieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-2'-methyl-, (16b)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5'H-Pregna-1,4,9(11)-trieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-2'-methyl-, (16b)- (9CI)(16119-56-5)
• EPA Substance Registry System: 5'H-Pregna-1,4,9(11)-trieno[17,16-d]oxazole-3,20-dione,21-(acetyloxy)-2'-methyl-, (16b)- (9CI)(16119-56-5)

Safety Data

• Hazardous Substances Data: 16119-56-5(Hazardous Substances Data)

Usage

Type

Synthetic derivative of progesterone

Structure

Steroid compound with modified oxazole ring at C17 and acetyloxy group at C21

Stereochemistry

(16b) designation indicates stereochemistry

Pharmaceutical Applications

Potential for interacting with progesterone receptors

Uses

Research and drug development for hormonal imbalances, reproductive health, and inflammation conditions.

Upstream product

• 13649-88-2 11β-hydroxy-2'-methyl-(16β)-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 
• 16119-50-9 3β-hydroxy-2'-methyl-(5α,16β)-pregnano[17,16-d]oxazole-11,20-dione 20-semicarbazone 
• 13649-85-9 3β,11β-dihydroxy-2'-methyl-(5α,16β)-pregnano[17,16-d]oxazol-20-one semicarbazone 
• 14927-19-6 11β-hydroxy-2'-methyl-(5α,16β)-pregnano[17,16-d]oxazole-3,20-dione 
• 13649-86-0 3β,11β-dihydroxy-2'-methyl-(5α,16β)-pregnano[17,16-d]oxazol-20-one 
• 19890-70-1 21-acetoxy-3β-hydroxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazol-20-one 
• 19890-68-7 3β-acetoxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazol-20-one 
• 13649-87-1 3β-acetoxy-11β-hydroxy-2'-methyl-(5α,16β)-pregnano[17,16-d]oxazol-20-one 
• 19890-69-8 3β-hydroxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazol-20-one 
• 14484-47-0 deflazacort 
• 19890-71-2 21-acetoxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazole-3,20-dione 

Downstream Products

• 19890-66-5 21-acetoxy-9-bromo-11β-hydroxy-2'-methyl-(16β)-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 
• 14484-47-0 deflazacort 
• 13649-57-5 21-Deacetyldeflazacort 
• 19888-56-3 21-acetoxy-9-fluoro-11β-hydroxy-2'-methyl-(16β)-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 

Relevant articles and documents

Steroids possessing nitrogen atoms. 3. Synthesis of new highly active corticoids. [17-alpha, 16-alpha-d]oxazolino steroids.

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