16120-92-6

Basic information

• Product Name: H-MET-NH2 HCL
• Synonyms: METHIONINE-NH2 HCL;L-METHIONINE AMIDE HYDROCHLORIDE;L-METHIONINE AMIDE HYDROCHLORIDE SALT;L-METHIONINAMIDE HYDROCHLORIDE;H-MET-NH2 HCL;H-L-MET-NH2 HCL;l-methioninamidehcl;L-Methioninamide
• CAS NO: 16120-92-6
• Molecular Formula: C₅H₁₃N₂OS*Cl
• Molecular Weight: 184.69
• Product Categories: Amino Acid Derivatives;Amino Acids;Amino hydrochloride
• Mol File: 16120-92-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 160-162 °C (decomp)(Solv: ethanol (64-17-5))
• Boiling Point: 351.8 °C at 760 mmHg
• Flash Point: 166.6 °C
• Appearance: /
• Vapor Pressure: 2.81E-05mmHg at 25°C
• Storage Temp.: Store at RT.
• CAS DataBase Reference: H-MET-NH2 HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-MET-NH2 HCL(16120-92-6)
• EPA Substance Registry System: H-MET-NH2 HCL(16120-92-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 16120-92-6(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C5H12N2OS.ClH/c1-9-3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H2,7,8);1H

Upstream product

• 34805-23-7 (S)-N-(tert-butoxycarbonyl)methionine amide 
• 6810-12-4 s-methionine hydrochloride 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 84890-95-9 C₁₅H₂₇NO₆S 

Downstream Products

• 2280-68-4 N-tert-butoxycarbonyl-L-leucyl-L-methioninamide 
• 111610-57-2 [(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester 
• 80768-13-4 Boc-Nip-Met-NH₂ 
• 66959-98-6 {[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester 
• 68800-26-0 N-tert-butoxycarbonylglycylglycylphenylalanylmethionine 
• 160693-25-4 N-t-butyloxycarbonyl-β-benzyl-aspartyl-methionine amide 
• 160693-26-5 Boc-Glu(OBzl)-Met-NH₂ 
• 71450-10-7 benzyl N-((1S)-2-[(1S)-1-(aminocarbonyl)-3-(methylsulfanyl)propyl]amino-1-benzyl-2-oxoethyl)carbamate 
• 1142-20-7 N-Cbz-Ala 
• 73148-99-9 N-t-Boc-Phe-Phe-Gly-Leu-Met-NH₂ 
• 1161-13-3 N-Cbz-L-Phe 

Relevant articles and documents

Methionine analogues as inhibitors of methionyl-tRNA synthetase

A series of methionine analogues have been synthesized as inhibitors of methionyl-tRNA synthetase and evaluated for their inhibitory activities of E. coli methionyl-tRNA synthetase and bacterial growth. Among them, L-methionine hydroxamate 20 has proved to be the best inhibitor of the enzyme with K(i) = 19 μM and showed a growth inhibition against E. coli JM 109, P. vulganis 6059 and C. freundii 8090.

Dichlorotris(dimethylamino)phosphorane as a Dehydratisation Reagent for the Preparation of N-Protected Amino Acid Amides

Besides for the synthesis of peptides and activated esters dichlorotris(dimethylamino)phosphorane (2) now proved to be an excellent reagent for the preparation of N-protected amino acid amides.