1612223-06-9

Basic information

• Product Name: (R)-1-phenylethyl (2S)-2-(4-bromopyridin-2-yl)propanoate
• CAS NO: 1612223-06-9
• Molecular Weight: 334.213
• Mol File: 1612223-06-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-phenylethyl (2S)-2-(4-bromopyridin-2-yl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-phenylethyl (2S)-2-(4-bromopyridin-2-yl)propanoate(1612223-06-9)
• EPA Substance Registry System: (R)-1-phenylethyl (2S)-2-(4-bromopyridin-2-yl)propanoate(1612223-06-9)

Safety Data

• Hazardous Substances Data: 1612223-06-9(Hazardous Substances Data)

Upstream product

• 1120-87-2 4-bromopyridin 
• 14248-50-1 4-bromopyridine-1-oxide 
• 1612223-03-6 (R,E)-trimethyl((1-(1-phenylethoxy)prop-1-en-1-yl)oxy)silane 

Relevant articles and documents

Expedient synthesis of α-(2-azaheteroaryl) acetates via the addition of silyl ketene acetals to azine- N -oxides

A new and expedient synthesis of α-(2-azaheteroaryl) acetates is presented. The reaction proceeds rapidly under mild conditions via the addition of silyl ketene acetals to azine-N-oxides in the presence of the phosphonium salt PyBroP. This procedure affords diverse α-(2-azaheteroaryl) acetates which are highly desirable components/building blocks in molecules of pharmaceutical interest but are traditionally challenging to synthesize via contemporary methods. The reaction optimization and mechanism as well as a novel electronically enhanced PyBroP derivative are described.