161271-00-7

Basic information

• Product Name: Methyl 2-isocyano-2,2-diphenylacetate
• Synonyms: Methyl 2-isocyano-2,2-diphenylacetate
• CAS NO: 161271-00-7
• Molecular Weight: 251.285
• Mol File: 161271-00-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methyl 2-isocyano-2,2-diphenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-isocyano-2,2-diphenylacetate(161271-00-7)
• EPA Substance Registry System: Methyl 2-isocyano-2,2-diphenylacetate(161271-00-7)

Safety Data

• Hazardous Substances Data: 161271-00-7(Hazardous Substances Data)

Upstream product

• 3060-50-2 2,2-diphenylglycine 
• 183734-04-5 formylamino-diphenyl-acetic acid 
• 210835-69-1 N-Formyl-α,α-diphenylglycine methyl ester 

Relevant articles and documents

Synthesis of tripeptides containing α,α-diphenylglycine by the modified Ugi reaction

The modified Ugi reaction has been developed to synthesize tripeptides containing α,α-diphenylglycine (Dph) together with bulky amino acids. By the use of diphenylmethanimine, N-benzyloxycarbonyl (Z) amino acids and isocyanides derived from amino acids, very crowded tripeptides such as Z- Aib-Dph-Aib-OMe, Z-Ac6c-Dph-Aib-OMe, Z-Dph-Dph-Dph-OMe, etc. have been synthesized.