1613073-72-5

Basic information

• Product Name: N-benzyl-2-nitro-N-(m-tolyl)acetamide
• Synonyms: N-benzyl-2-nitro-N-(m-tolyl)acetamide
• CAS NO: 1613073-72-5
• Molecular Weight: 284.315
• Mol File: 1613073-72-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-2-nitro-N-(m-tolyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-2-nitro-N-(m-tolyl)acetamide(1613073-72-5)
• EPA Substance Registry System: N-benzyl-2-nitro-N-(m-tolyl)acetamide(1613073-72-5)

Safety Data

• Hazardous Substances Data: 1613073-72-5(Hazardous Substances Data)

Upstream product

• 625-75-2 nitroacetic acid 
• 5405-17-4 N-benzyl-3-methylaniline 

Downstream Products

• 1613073-85-0 N³,N⁶-dibenzyl-N³,N⁶-di(m-tolyl)-1,4,2,5-dioxadiazine-3,6-dicarboxamide 

Relevant articles and documents

Cascade nitrosation and addition-elimination of nitroacetanilides for the highly efficient synthesis of 1,4,2,5-dioxadiazine derivatives

A domino nitrosation and addition-elimination of nitroacetanilides with NaNO2 and H2SO4 has been developed to synthesize a variety of 1,4,2,5-dioxadiazine-3,6-dicarboxamides in excellent yields. The substrate scope can be extended to aryl nitromethyl ketones. A cascade reaction mechanism is proposed and the conjugated aryl moiety is considered to help stabilize the aci-nitroso species, the key intermediates in the cascade reaction. The methodology is practical and efficient because it avoids the purification of the intermediates. The nitroacetanilides were prepared from nitroacetic acid and various anilines employing DCC-DMAP as coupling reagents, and this protocol also possesses advantages like easy handling and high yields. This journal is the Partner Organisations 2014.