16135-32-3Relevant articles and documents
AN EFFECTIVE METHOD FOR FORMYLATION OF WEAKLY NUCLEOPHILIC ANILINES AND INDOLE
Shiina, Isamu,Miyashita, Mitsutomo,Nagai, Masashi,Mukaiyama, Teruaki
, p. 141 - 148 (2007/10/02)
In the presence of a catalytic amount of active titanium(IV) salt or Yb(OTf)3, weakly nucleophilic anilines and indole react under mild conditions with formic acid or aqueous formic acid to afford respectively the corresponding formanilides and indole-3-carboxaldehyde in excellent yields using 4-trifluoromethylbenzoic anhydride as a coreagent.