1613810-31-3

Basic information

• Product Name: diethyl 9-(4-chlorobenzoyl)-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,3]-diazepine-7,8-dicarboxylate
• Synonyms: diethyl 9-(4-chlorobenzoyl)-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,3]-diazepine-7,8-dicarboxylate
• CAS NO: 1613810-31-3
• Molecular Weight: 418.877
• Mol File: 1613810-31-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 9-(4-chlorobenzoyl)-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,3]-diazepine-7,8-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 9-(4-chlorobenzoyl)-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,3]-diazepine-7,8-dicarboxylate(1613810-31-3)
• EPA Substance Registry System: diethyl 9-(4-chlorobenzoyl)-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,3]-diazepine-7,8-dicarboxylate(1613810-31-3)

Safety Data

• Hazardous Substances Data: 1613810-31-3(Hazardous Substances Data)

Upstream product

• 762-21-0 acetylenedicarboxylic acid diethyl ester 
• 42934-96-3 (E)-diethyl 2,3-diiodofumarate 
• 124927-46-4 1-(4-chlorophenyl)-2-(1,3-diazepan-2-ylidene)ethan-1-one 

Relevant articles and documents

Palladium(II)-catalyzed cyclization of heterocyclic ketene aminals with (E)-ethyl 2,3-diiodoacrylates: Selective synthesis of bicyclic pyrroles and bicyclic pyridones

A concise and efficient synthesis of novel bicyclic pyrroles has been achieved by PdCl2-catalyzed cyclic condensation of six-membered heterocyclic ketene aminals (HKAs) or seven-membered HKAs with ethyl 2,3-diiodoacrylate and diethyl 2,3-diiodofumarate in the presence of Cs 2CO3, respectively. A series of novel bicyclic pyridones have also been obtained via five-membered HKAs with diethyl 2,3-diiodofumarate under the optimized conditions in moderate yields. These reactions are the first application of a transition metal to catalyze the building blocks HKAs to form the bicyclic pyrrole library via condensation reaction.