16141-18-7

Basic information

• Product Name: 4-ETHYNYLPHENYL ACETATE
• Synonyms: 4-ETHYNYLPHENYL ACETATE
• CAS NO: 16141-18-7
• Molecular Formula: C₁₀H₈O₂
• Molecular Weight: 160.16932
• Mol File: 16141-18-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 234.444°C at 760 mmHg
• Flash Point: 89.477°C
• Appearance: /
• Density: 1.114g/cm³
• Vapor Pressure: 0.053mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: 4-ETHYNYLPHENYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHYNYLPHENYL ACETATE(16141-18-7)
• EPA Substance Registry System: 4-ETHYNYLPHENYL ACETATE(16141-18-7)

Safety Data

• Hazardous Substances Data: 16141-18-7(Hazardous Substances Data)

Usage

Description

4-Ethynylphenyl acetate, with the chemical formula C10H8O2, is an aromatic ester known for its strong aromatic properties. It is a colorless to pale yellow liquid with a characteristic odor and is commonly used in the synthesis of organic compounds and pharmaceuticals.

Uses

Used in Pharmaceutical Industry:
4-Ethynylphenyl acetate is used as an intermediate in the synthesis of various pharmaceuticals due to its versatile chemical structure and reactivity.
Used in Flavoring and Fragrance Industry:
4-Ethynylphenyl acetate is used as a flavoring agent in the food and beverage industry, adding unique aromatic notes to products.
Used in Material Science:
4-Ethynylphenyl acetate is used in the development of new materials such as polymers and coatings, leveraging its strong aromatic properties and potential for chemical modification.

InChI:InChI=1/C10H8O2/c1-3-9-4-6-10(7-5-9)12-8(2)11/h1,4-7H,2H3

Upstream product

• 33527-94-5 4-acetoxyiodobenzene 
• 165825-13-8 4-((2-trimethylsilyl)ethynyl)phenyl acetate 
• 540-38-5 p-Iodophenol 
• 1927-95-3 4-bromophenyl acetate 

Downstream Products

• 136781-96-9 rubrolide D diacetate 
• 1028293-57-3 (Z)-7-{(1S,2R,3R,4R)-3-[4-(4-Acetoxy-phenylethynyl)-3-nitro-benzenesulfonylamino]-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester 
• 557792-50-4 (Z)-7-{(1S,2R,3R,4R)-3-[2-(4-Acetoxy-phenyl)-1H-indole-6-sulfonylamino]-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester 
• 1029361-16-7 4-{2-[4-(2-trifluoromethylbenzoyl)piperazin-1-yl]pyrimidin-5-ylethynyl}-phenyl acetate 
• 1029361-18-9 3-{2-[4-(2-trifluoromethylbenzoyl)piperazin-1-yl]pyrimidin-5-ylethynyl}phenyl acetate 
• 1029359-18-9 4-{[6-(4-benzyl-4-hydroxypiperidin-1-yl)pyridazin-3-yl]ethynyl}phenyl acetate 
• 1029361-22-5 4-{6-[4-(2-fluorobenzyl-4-hydroxypiperidin-1-yl)pyridazin-3-yl]ethynyl}phenyl acetate 
• 1029359-24-7 4-{[6-(4-hydroxy-4-(2,5-dichlorobenzyl)piperidin-1-yl)pyridazin-3-yl]ethynyl}phenyl acetate 
• 1029359-28-1 4-[{6-[3-(2-fluorophenoxy)azetidin-1-yl]pyridazin-3-yl}ethynyl]phenyl acetate 
• 1029359-46-3 4-[{6-[4-(2-fluorophenoxy)piperidin-1-yl]pyridazin-3-yl}ethynyl]phenyl acetate 
• 1029359-94-1 4-[(6-{2-[(2-fluorophenoxy)ethyl]amino}pyridazin-3-yl)ethynyl]phenyl acetate 
• 1029359-98-5 4-({[6-[4-(2-fluorophenylamino)piperidin-1-yl]pyridazin-3-yl]pyridazin-3-yl}ethynyl)-phenyl acetate 
• 1127897-08-8 (E)-2-(2-diethylaminoethyl)-3-(4-hydroxybenzylidene)-2,3-dihydro-isoindol-1-one 
• 1186419-62-4 1-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-4-(p-acetoxyphenyl)-1,2,3-triazole 

Relevant articles and documents

Hydrosoluble and solvatochromic naphthalene diimides with NIR absorption

Mimicking biochromophore anions containing phenolate moieties, eight conjugated naphthalene diimides (NDIs) have been synthesized in order to develop probes, displaying charge-transfer transitions affected by the nearby environment. NIR absorption of the resulting phenolates and their solvatochromic properties in both organic solvents and water are described.

Regio- and stereoselective synthesis of bromoalkenes by homolytic hydrobromination of alkynes with hydrogen bromide

Homolytic hydrobromination of terminal and internal alkynes with a commercially available solution of hydrogen bromide in acetic acid has been investigated for regio- and stereoselective synthesis of bromoalkenes. Under an aerobic atmosphere at room temperature, the reaction of ethynylarenes with a small excess of HBr efficiently gave (2-bromoethenyl)arenes with good to high E-selectivity. (Alk-1-ynyl)arenes, or internal alkynes bearing both phenyl and alkyl groups at the sp-carbons also underwent the air-initiated hydrobromination to exhibit high Z-selectivity under kinetic conditions using a half equivalent of HBr.

Cobalt-Catalyzed Hydroalkynylation of Vinylaziridines

Transition metal-catalyzed hydroalkynylation reactions are efficient transformations allowing the straightforward formation of functionalized alkynes. Therein, we disclose the cobalt-catalyzed hydroalkynylation of vinylaziridines giving rise to both linea