16143-07-0

Basic information

• Product Name: (E)-2-(4-chlorostilben-4'-yl)-1,3-benzoxazole
• Synonyms: (E)-2-(4-chlorostilben-4'-yl)-1,3-benzoxazole
• CAS NO: 16143-07-0
• Molecular Weight: 331.801
• Mol File: 16143-07-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-chlorostilben-4'-yl)-1,3-benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-chlorostilben-4'-yl)-1,3-benzoxazole(16143-07-0)
• EPA Substance Registry System: (E)-2-(4-chlorostilben-4'-yl)-1,3-benzoxazole(16143-07-0)

Safety Data

• Hazardous Substances Data: 16143-07-0(Hazardous Substances Data)

Upstream product

• 117649-27-1 2-(4-bromo-benzylidenamino)-phenol 
• 1073-67-2 4-vinylbenzyl chloride 
• 3164-13-4 2-(4-bromophenyl)-1,3-benzoxazole 
• 99-94-5 p-Toluic acid 
• 835-71-2 2-(4-methylphenyl)-1,3-benzoxazole 
• 2362-79-0 N-(4-chlorobenzylidene)aniline 
• 95-55-6 2-amino-phenol 

Relevant articles and documents

Facile access to libraries of diversely substituted 2-aryl-benzoxazoles/benzothiazoles from readily accessible aldimines via cyclization/cross coupling in imidazolium-ILs with Pd(OAc)2 or NiCl2 (dppp) as catalyst

A two-step protocol involving Pd-catalyzed cyclization of readily accessible p-bromophenyl-aldimines to 2-bromophenyl-benzoxazole/benzothiazole in [BMIM][PF6] or [BMIM][BF4] as solvent, followed by the Suzuki, Heck, and Sonogashira cross-coupling reactions catalyzed by Pd or Ni is described that generates libraries of diversely substituted 2-aryl-/heteroaryl-benzoxazoles/benzothiazoles in respectable isolated yields under mild reaction conditions. The feasibility to perform the two-steps in sequence in one-pot starting from the aldimines is also demonstrated and the potential for recycling/reuse of the IL solvent is also shown.