161465-86-7

Basic information

• Product Name: 4-amino-5-acetyl-2-methyl-4-phenylpyrimidine
• Synonyms: 4-amino-5-acetyl-2-methyl-4-phenylpyrimidine
• CAS NO: 161465-86-7
• Molecular Weight: 227.266
• Mol File: 161465-86-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-amino-5-acetyl-2-methyl-4-phenylpyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-5-acetyl-2-methyl-4-phenylpyrimidine(161465-86-7)
• EPA Substance Registry System: 4-amino-5-acetyl-2-methyl-4-phenylpyrimidine(161465-86-7)

Safety Data

• Hazardous Substances Data: 161465-86-7(Hazardous Substances Data)

Upstream product

• 56563-07-6 N-cyanoacetamidine 
• 93-91-4 1-phenylbutan-1,3-dione 

Downstream Products

• 354543-55-8 N-(5-acetyl-2-methyl-6-phenylpyrimidin-4-yl)-2-methylpropanamide 

Relevant articles and documents

Efficient method for the synthesis of pyridopyrimidin-5-ones from 4-amino-5-acetylpyrimidines

New method for annelation of a pyridine ring to a pyrimidine ring were suggested.Substituted 8H-pyridopyrimidin-5-ones (8a-f) were synthesized by the interaction of 2,6-disubstituted 4-amino-5-acetylpyrimidines (1-4) with formamide or acetamide acetals followed by cyclization under the action of sodium methoxide in methanol. 2,4-Disubstituted 7-phenyl-8H-pyridopyrimidin-5-ones (11a-c) were propared by the reaction of 2,6-disubstituted 5-acetyl-4-benzoylaminopyrimidines (10a-c) with MeONa in boiling BuOH. - Key words: 4-amino-5-acetylpyrimidines, 4-benzoylamino-5-acetylpyrimidines, dimethylformamide dimethylacetal, dimethylacetamide dimethylacetal, pyridopyrimidin-5-ones.