1615691-63-8

Basic information

• Product Name: (4S,5R)-4-phenyl-5-(thiophen-2-yl)-5-(thiophene-2-carbonyl)dihydrofuran-2(3H)-one
• CAS NO: 1615691-63-8
• Molecular Weight: 354.45
• Mol File: 1615691-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,5R)-4-phenyl-5-(thiophen-2-yl)-5-(thiophene-2-carbonyl)dihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-4-phenyl-5-(thiophen-2-yl)-5-(thiophene-2-carbonyl)dihydrofuran-2(3H)-one(1615691-63-8)
• EPA Substance Registry System: (4S,5R)-4-phenyl-5-(thiophen-2-yl)-5-(thiophene-2-carbonyl)dihydrofuran-2(3H)-one(1615691-63-8)

Safety Data

• Hazardous Substances Data: 1615691-63-8(Hazardous Substances Data)

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 27761-02-0 thenoin 

Relevant articles and documents

One-pot asymmetric synthesis of substituted tetrahydrofurans via a multicatalytic benzoin/Michael/acetalization cascade

A sequential benzoin/Michael/acetalization tandem reaction catalyzed by NHC and amine together has been developed to assemble aromatic aldehydes and enals into chiral tetrahydrofuran derivatives bearing multiple functional groups and stereogenic centers with high stereoselectivity of up to 95:5 dr and 96% ee. The high yield and stereocontrol of this process may be due to both acid-promoted symmetrization of racemic acyloins and iminium ion activation of enals.