161675-43-0Relevant articles and documents
Process for producing cephalosporin derivatives
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, (2008/06/13)
The present invention is concerned with a novel process for the manufacture of cephalosporin derivatives of the formula by converting a phosphonium salt into the corresponding ylide and reacting same with an aldehyde wherein R1 and R2 /su
Synthesis and structure-activity relationship of (lactamylvinyl)cephalosporins exhibiting activity against staphylococci, pneumococci, and enterococci
Heinze-Krauss, Ingrid,Angehrn, Peter,Guerry, Philippe,Hebeisen, Paul,Hubschwerlen, Christian,Kompis, Ivan,Page, Malcolm G. P.,Richter, Hans G. F.,Runtz, Valérie,Stalder, Henri,Weiss, Urs,Wei, Chung-Chen
, p. 1864 - 1871 (2007/10/03)
The synthesis and structure-activity relationships of a new class of vinylcephalosporins substituted with a lactamyl residue (1) are described. These compounds show excellent activity against enterococci and retain the broad spectrum activity of third-gen