161886-21-1

Basic information

• Product Name: Benzonitrile, 2-fluoro-5-hydrazino- (9CI)
• Synonyms: Benzonitrile, 2-fluoro-5-hydrazino- (9CI);2-Fluoro-5-(hydrazino)benzonitrile;4-Fluoro-3-cyanophenylhydrazine;2-fluoro-5-hydrazinylbenzonitrile;Benzonitrile, 2-fluoro-5-hydrazino-
• CAS NO: 161886-21-1
• Molecular Formula: C₇H₆FN₃
• Molecular Weight: 151.1410432
• Product Categories: HYDRAZINE;HALIDE
• Mol File: 161886-21-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 280℃
• Flash Point: 123℃
• Appearance: /
• Density: 1.30
• Storage Temp.: 2-8°C
• PKA: 4.53±0.24(Predicted)
• CAS DataBase Reference: Benzonitrile, 2-fluoro-5-hydrazino- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 2-fluoro-5-hydrazino- (9CI)(161886-21-1)
• EPA Substance Registry System: Benzonitrile, 2-fluoro-5-hydrazino- (9CI)(161886-21-1)

Safety Data

• Hazardous Substances Data: 161886-21-1(Hazardous Substances Data)

Usage

General Description

Benzonitrile, 2-fluoro-5-hydrazino- (9CI) is a chemical compound with the molecular formula C7H5FN3. It is a derivative of benzonitrile with a fluorine atom and a hydrazino group attached to the aromatic ring. Benzonitrile, 2-fluoro-5-hydrazino- (9CI) is used in the pharmaceutical and chemical industry as a building block for the synthesis of various organic compounds. It has potential applications in the development of pharmaceutical drugs and agrochemicals due to its unique chemical properties. Additionally, it is used as a reagent in organic synthesis and research laboratories. However, it is important to handle this compound with caution as it may have hazardous properties.

Upstream product

• 53312-81-5 3-cyano-4-fluoroaniline 
• 1020174-08-6 C₇H₃FN₃⁽¹⁺⁾*Cl^(1-) 

Downstream Products

• 543745-11-5 1-(3-cyano-4-fluoro)phenyl-3-trifluoromethyl-6-(4-iodo)phenyl-1,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridin-7-one 
• 905931-55-7 2-fluoro-5-[6-(2-fluoro-4-iodo-phenyl)-7-oxo-3-trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[3,4-c]pyridin-1-yl]-benzonitrile 
• 280120-37-8 2-fluoro-5-[6-(2'-formyl-biphenyl-4-yl)-3-methyl-7-oxo-4,5,6,7-tetrahydro-pyrazolo[3,4-c]pyridin-1-yl]-benzonitrile 
• 543745-12-6 1-(3-Cyano-4-fluoro)phenyl-3-trifluoromethyl-6-[4-(2-formyl)phenyl]phenyl-1,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridin-7-one 
• 280120-51-6 2-fluoro-5-[6-(3-fluoro-2'-formyl-biphenyl-4-yl)-7-oxo-3-trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[3,4-c]pyridin-1-yl]-benzonitrile 

Relevant articles and documents

FACTOR XA COMPOUNDS

The present invention is directed to novel compounds of Formula (I) and forms and pharmaceutical compositions thereof, and the use thereof as inhibitors of Factor Xa.

Process for the preparation of 1,3,5-trisubstituted pyrazoles via [3+2] cycloaddition

A process for the preparation of 1,3,5-trisubstituted pyrazole compounds, which are useful intermediates in the synthesis of factor Xa inhibitors.

Herbicides

The invention provides compounds of formula: wherein R and R1 independently represent hydrogen, optionally halogenated alkyl alkenyl or alkynyl;, -(-CR3R4)n-(optionally subtituted phenyl); -(-CR3R4)nHet; or, -(-CR3R4)n-Ar, wherein Ar is an optionally substituted bicycle;, wherein at least one of the groups R and R1 represents -(-CR3R4)n-Ar;, R2 represents R5 or optionally substituted phenyl;, X is oxygen or sulphur; m is 0, 1, 2 or 3;, R3 and R4, independently represent hydrogen, alkyl or haloalkyl;, R5 is halogen, optionally halogenated alkyl, alkenyl or alkynyl;, or a group selected from cyano, nitro, -CO2R6, -S(O)pR6, -NR3R4, -COR6, -S(O)pR7, -CO2R7, -OR7, -CONR3R4, -OSO2R7, -OSO2R8, -OCH2R7, -N(R3)COR8, -N(R3)SO2R8, -N(R3)SO2R7, -SO2NR3R4, -Si(R8)3 and -OR6;, n is zero, 1 or 2; q is zero or an integer from 1 to 5;, Het represents an optionally substituted heterocycle;, R6 represents hydrogen, alkyl or haloalkyl;, p is zero, one or two; r is one or two;, R7 represents optionally substituted phenyl;, R8 represents alkyl or haloalkyl;, R61 and R62 independently represent hydrogen, halogen, alkyl or haloalkyl;, and agriculturally acceptable salts thereof;, which possess utility as herbicides.