161886-60-8 Usage
Description
(S)-CARNITINE MESYLATE, MESLATE SALT, also known as (S)-Carnitine Methyl Ester Hydrochloride, is an organic compound with the CAS number 161886-60-8. It is characterized by its off-white solid appearance and is primarily used in organic synthesis.
Uses
Used in Pharmaceutical Industry:
(S)-CARNITINE MESYLATE, MESLATE SALT is used as an intermediate compound for the synthesis of various pharmaceutical products. Its role in organic synthesis allows for the creation of a wide range of medications, contributing to the development of new treatments and therapies.
Used in Nutritional Supplements:
(S)-CARNITINE MESYLATE, MESLATE SALT is also utilized as a key ingredient in the formulation of nutritional supplements. It plays a vital role in energy production and supports overall health and well-being.
Used in Organic Synthesis:
(S)-CARNITINE MESYLATE, MESLATE SALT is used as a reagent in organic synthesis for the production of various organic compounds. Its versatility in chemical reactions makes it a valuable component in the synthesis of a diverse array of molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 161886-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,8,8 and 6 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 161886-60:
(8*1)+(7*6)+(6*1)+(5*8)+(4*8)+(3*6)+(2*6)+(1*0)=158
158 % 10 = 8
So 161886-60-8 is a valid CAS Registry Number.
161886-60-8Relevant articles and documents
The β-Lactone Route to a Totally Stereoselective Synthesis of Carnitine Derivatives
Bernabei, Ida,Castagnani, Roberto,Angelis, Francesco De,Fusco, Enrico De,Gianessi, Fabio,et al.
, p. 826 - 831 (2007/10/03)
The syntheses of the enantiomerically pure, carnitine-related β-lactones 10 and 12 starting from various carnitine precursors of opposite configuration (or carnitine itself) are described. (R)-3-Chlorocarnitine (20) has also been directly prepared from (S)-carnitine (14) and has been cyclized to 12 by a second inversion of configuration of the stereogenic centre.By nucleophilic attack at the carbonyl carbon, the β-lactone carnitine derivatives have been converted into esters, amides, and guanidino congeners.Following this route, it is possible to obtain the biologically active isomer (R)-carnitine (1) starting from the otherwise useless industrial by-product (S)-carnitine (14).Nucleophilic attack by selected ambident nucleophiles at the β-carbon of the same β-lactone derivatives results in a second inversion of configuration of the stereogenic centre.Besides aminocarnitine (3), chiral acetylcarnitine (2) and acetylthiocarnitine (5) have been synthesized in homochiral forms following this latter procedure. - Keywords: asymmetric ring-opening; carnitine; cyclizations; β-lactones; nucleophilic substitutions
