1619-62-1

Basic information

• Product Name: DIETHYL DIMETHYLMALONATE
• Synonyms: 2,2-dimethyl-malonicaciddiethylester;Diethyl 2,2-dimethylmalonate;Malonic acid, dimethyl-, diethyl ester;DIETHYL DIMETHYLMALONATE;Dimethylmalonic Acid Diethyl Ester;2,2-Dimethylpropanedioic acid diethyl ester;Diethyl dimethylmalonate,97%;Propanedioic acid, 2,2-diMethyl-, 1,3-diethyl ester
• CAS NO: 1619-62-1
• Molecular Formula: C₉H₁₆O₄
• Molecular Weight: 188.22
• EINECS: 216-582-6
• Product Categories: Pharmaceutical Intermediates;C8 to C9;Carbonyl Compounds;Esters
• Mol File: 1619-62-1.mol
• Article Data: 30

Chemical Properties

• Melting Point: -30.4°C
• Boiling Point: 192 °C(lit.)
• Flash Point: 160 °F
• Appearance: Clear colorless/Liquid
• Density: 0.991 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.387mmHg at 25°C
• Refractive Index: n20/D 1.412(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: DIETHYL DIMETHYLMALONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL DIMETHYLMALONATE(1619-62-1)
• EPA Substance Registry System: DIETHYL DIMETHYLMALONATE(1619-62-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-52/53
• Safety Statements: 24/25-61
• WGK Germany: 3
• Hazardous Substances Data: 1619-62-1(Hazardous Substances Data)

Usage

Description

DIETHYL DIMETHYLMALONATE is a clear, colorless liquid that forms adducts with α,α,α′,α′-tetraaryl-1,3-dioxolane-4,5-dimethanol based titanium catalysts. It is a chemical compound with various applications across different industries.

Uses

Used in Chemical Industry:
DIETHYL DIMETHYLMALONATE is used as a reagent for the synthesis of various organic compounds. Its ability to form adducts with titanium catalysts makes it a valuable component in the production of different chemical products.
Used in Pharmaceutical Industry:
DIETHYL DIMETHYLMALONATE is used as an intermediate in the synthesis of pharmaceutical compounds. Its unique chemical properties allow it to be a key component in the development of new drugs and medications.
Used in Plastics and Polymer Industry:
DIETHYL DIMETHYLMALONATE is used as a monomer in the production of certain types of plastics and polymers. Its versatility in forming adducts with various catalysts contributes to the development of new materials with specific properties.
Used in Coatings Industry:
DIETHYL DIMETHYLMALONATE is used as a component in the formulation of coatings, such as paints and varnishes. Its chemical properties help improve the performance and durability of these coatings.
Used in Lubricants Industry:
DIETHYL DIMETHYLMALONATE is used as an additive in the formulation of lubricants, enhancing their performance and reducing friction in various applications.

InChI:InChI=1/C9H16O4/c1-5-12-7(10)9(3,4)8(11)13-6-2/h5-6H2,1-4H3

Upstream product

• 60-29-7 diethyl ether 
• 873421-52-4 3-methyl-hexane-2,2,4-tricarboxylic acid triethyl ester 
• 141-52-6 sodium ethanolate 
• 5659-97-2 dimethyl-malonyl bromide 
• 541-41-3 chloroformic acid ethyl ester 
• 97-62-1 Ethyl isobutyrate 
• 77-78-1 dimethyl sulfate 
• 105-53-3 diethyl malonate 
• 74-88-4 methyl iodide 
• 854462-99-0 2-methyl-butane-1,3,3-tricarboxylic acid triethyl ester 
• 996-82-7 sodium diethylmalonate 
• 10319-92-3 3,3,5,5-tetramethyl-6-(propan-2-ylidene)-dihydro-3H-pyran-2,4-dione 
• 933-52-8 2,2,4,4-tetramethyl-1,3-cyclobutanedione 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 96-22-0 pentan-3-one 
• 79-31-2 isobutyric Acid 
• 594-88-7 3-hydroxy-2,2,3-trimethylbutanoic acid 
• 1888-57-9 2,5-dimethylhexan-3-one 
• 108-83-8 diisobutyl ketone 
• 589-55-9 heptan-4-ol 
• 2198-72-3 4-propylheptan-4-ol 
• 7379-12-6 n-propyl isopropyl ketone 
• 123-19-3 4-heptanone 
• 97-62-1 Ethyl isobutyrate 
• 19424-43-2 2,3,3,4-tetramethylpentane-2,4-diol 
• 62817-86-1 3-hydroxy-2,2,3-trimethyl-butyric acid ethyl ester 
• 67-64-1 acetone 
• 57186-07-9 4,4-dimethyl-1-phenylpyrazolidine-3,5-dione 

Relevant articles and documents

REACTION MECHANISMS FOR ELECTROCHEMICAL CARBON-SKELETON REARRANGEMENT AS CATALYZED BY HYDROPHOBIC VITAMIN B12 IN NONAQUEOUS MEDIA

Reaction mechanisms for the controlled-potential electrolysis of 2,2-bis(ethoxycarbonyl)-1-bromopropane at -1.0, -1.5, and -2.0 V vs.SCE as catalyzed by a hydrophobic vitamin B12 were clarified.

A Convenient Synthesis of Diethyl Dialkyl- and Dibenzylmalonates via Extractive Alkylation

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Methylcorrinoids methylate radicals - Their second biological mode of action?

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Characterization of a Simple Vitamin B12 Model Complex and Its Catalysis in Electrochemical Carbon-Skeleton Rearrangement

The electrochemical carbon-skeleton rearrangement reaction of 2,2-bis(ethoxycarbonyl)-1-bromopropane was catalyzed by the cobalt complex of 2,10-diethyl-3,9-dipropyl-1,4,8,11-tetraazaundeca-1,3,8,10-tetraene-1,10-diol, which was characterized by ESR spectroscopy and cyclic voltammetry.

Process for the alkylation of active methylene compounds

The invention discloses an alkylation method of an active methylene compound. The method comprises the following steps: A, adding the active methylene compound to an inorganic alkali-first polar organic solvent mixing system to form a to-be-reacted mixture; B, adding an alkylating agent to the to-be-reacted mixture, filtering after reacting to obtain filtrate, and removing a solvent in the filtrate to obtain the alkylated active methylene compound. According to the method, the inorganic alkali is adopted as a proton abstraction reagent of the active methylene compound, so that the removal effect on alpha-hydrogen in the active methylene compound can be ensured, the alkylation reaction of the active methylene compound can be carried out under a mild condition, and the reaction safety is improved. Meanwhile, the inorganic alkali is low in price, so that the production cost of the alkylation reaction is reduced.