1620098-31-8Relevant articles and documents
Design, synthesis and pharmacological evaluation of novel polycyclic heteroarene ethers as PDE10A inhibitors: Part II
Das, Sanjib,Shelke, Dnyaneshwar E.,Harde, Rajendra L.,Avhad, Vijayshree B.,Khairatkar-Joshi, Neelima,Gullapalli, Srinivas,Gupta, Praveen K.,Gandhi, Maulik N.,Bhateja, Deepak K.,Bajpai, Malini,Joshi, Ashwini A.,Marathe, Megha Y.,Gudi, Girish S.,Jadhav, Satyawan B.,Mahat, Mahamad Yunnus A.,Thomas, Abraham
supporting information, p. 3238 - 3242 (2014/07/22)
We report the design and synthesis of novel pyrrolo[3,2-b]quinoline containing heteroarene ethers as PDE10A inhibitors with good to excellent potency, selectivity and metabolic stability. Further optimization of this primary series resulted in the identif