162019-91-2Relevant articles and documents
GLYCOLIPID ANALOGS
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, (2008/06/13)
The present invention provides a compound which is a glycolipid analog having a novel structure represented by the formula (1): wherein Z represents an imino group, an oxygen atom or a sulfur atom; m is an integer of from 3 to 12; and n is an integer of from 4 to 22; and shows a potent activity of inhibiting glycosidase and has potential physiological activities, for example, antiviral activity. The invention also provides a glycosidase inhibitor which comprises said glycolipid analog as an active ingredient
Synthesis of glucosylceramide analogues. Imino-linked 5a-carbaglycosylceramides, potent and specific glucocerebrosidase inhibitors
Ogawa,Tsunoda,Inokuchi
, p. 1317 - 1318 (2007/10/02)
Imino-linked carbocyclic analogues (E)- and (Z)-2 of glucosylceramide 1 have been synthesized and shown to be potent and specific inhibitors against glucocerebrosidase.