1620401-54-8

Basic information

• Product Name: (S)-6-methylamino-2-methylheptene
• Synonyms: (S)-6-methylamino-2-methylheptene
• CAS NO: 1620401-54-8
• Molecular Weight: 141.257
• Mol File: 1620401-54-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-6-methylamino-2-methylheptene(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-6-methylamino-2-methylheptene(1620401-54-8)
• EPA Substance Registry System: (S)-6-methylamino-2-methylheptene(1620401-54-8)

Safety Data

• Hazardous Substances Data: 1620401-54-8(Hazardous Substances Data)

Upstream product

• 74-89-5 methylamine 
• 58917-27-4 (R)-sulcatol 

Downstream Products

• 7492-31-1 (S)-isometheptene mucate 

Relevant articles and documents

ISOMETHEPTENE ISOMER

The invention relates to a purified Isometheptene compound comprising the structure according to Formula (I), or a hydrochloride, or a pharmaceutically acceptable addition salt thereof. In particular, the disclosure relates to the synthesis, purification and characterization of an Isometheptene isomer mucate crystal 2, wherein the Isometheptene isomer 2 is stereochemically characterized as (R)-enantiomer, respectively. The Isometheptene (R)-enantiomer activity indicates a selective centrally acting selective ligand for Imidazoline subtype 1 (I1) receptor sites; and more specifically, the disclosure provides an antihypertensive composition for treatment of migraine and other neurovascular or neurogenic pain from abdominal distress. (R)-Isometheptene enantiomer or isomer 2 may be an anti-hypertensive agent with lower side effects than the racemate form. Therefore (R)-Isometheptene is believed to be effective against episodic tension-type headaches (ETTH). The (R)-Isometheptene enantiomer or isomer 2 is believed to effectively lower blood pressure, used alone or together with other headache ameliorating drugs. Methods of synthesis and treatment are described. Regarding (R)-Isometheptene crystals data of X-ray crystallography are presented.