1620581-44-3

Basic information

• Product Name: tert-butyl 1-((3-(4-cyano-2,6-dimethylheptan-4-yl)-4-methoxyphenyl)sulfonyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate
• CAS NO: 1620581-44-3
• Molecular Weight: 609.83
• Mol File: 1620581-44-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 1-((3-(4-cyano-2,6-dimethylheptan-4-yl)-4-methoxyphenyl)sulfonyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 1-((3-(4-cyano-2,6-dimethylheptan-4-yl)-4-methoxyphenyl)sulfonyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate(1620581-44-3)
• EPA Substance Registry System: tert-butyl 1-((3-(4-cyano-2,6-dimethylheptan-4-yl)-4-methoxyphenyl)sulfonyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate(1620581-44-3)

Safety Data

• Hazardous Substances Data: 1620581-44-3(Hazardous Substances Data)

Upstream product

• 1620581-25-0 C₁₇H₂₅NO 
• 7035-03-2 2-methoxy-benzeneacetonitrile 
• 1620581-27-2 C₁₇H₂₄ClNO₃S 
• 180465-84-3 2-methylpropan-2-yl 1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxylate 

Downstream Products

• 1620580-60-0 (E)-tert-butyl 1-((3-(4-cyano-2,6-dimethylheptan-4-yl)-4-methoxyphenyl)sulfonyl)-6-(3-ethoxy-3-oxoprop-1-en-1-yl)spiro[indoline-3,4'-piperidine]-1'-carboxylate 

Relevant articles and documents

Pd(II)-catalyzed meta-C-H olefination, arylation, and acetoxylation of indolines using a U-shaped template

meta-C-H olefination, arylation, and acetoxylation of indolines have been developed using nitrile-containing templates. The combination of a monoprotected amino acid ligand and the nitrile template attached at the indolinyl nitrogen via a sulfonamide linkage is crucial for the meta-selective C-H functionalization of electron-rich indolines that are otherwise highly reactive toward electrophilic palladation at the para-positions. A wide range of synthetically important and advanced indoline analogues are selectively functionalized at the meta-positions.