1620758-34-0 Usage
Description
(3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol is a complex organic compound with a unique molecular structure. It is characterized by its stereochemistry, with four chiral centers at the 3R, 4S, 5S, and 6R positions. (3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol is derived from a tetrahydrofuran core, which is further modified with various functional groups, including a chlorophenyl and hydroxymethyl group. Its specific structure and functional groups may endow it with potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol is used as a potential pharmaceutical compound for the development of new drugs. Its unique structure and functional groups may allow it to interact with specific biological targets, making it a promising candidate for the treatment of various diseases.
Used in Chemical Research:
(3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol can also be used as a research tool in the field of organic chemistry. Its synthesis and modification can provide insights into the development of new synthetic methods and the study of its reactivity with various reagents. Additionally, its stereochemistry and functional groups can be investigated for potential applications in asymmetric catalysis and enantioselective synthesis.
Used in Material Science:
The unique structure of (3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol may also find applications in the field of material science. Its functional groups can be exploited to design new materials with specific properties, such as improved mechanical strength, thermal stability, or chemical resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 1620758-34-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,0,7,5 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1620758-34:
(9*1)+(8*6)+(7*2)+(6*0)+(5*7)+(4*5)+(3*8)+(2*3)+(1*4)=160
160 % 10 = 0
So 1620758-34-0 is a valid CAS Registry Number.
1620758-34-0Relevant articles and documents
Efficient synthesis of empagliflozin, an inhibitor of SGLT-2, utilizing an AlCl3-promoted silane reduction of a β-glycopyranoside
Wang, Xiao-Jun,Zhang, Li,Byrne, Denis,Nummy, Larry,Weber, Dirk,Krishnamurthy, Dhileep,Yee, Nathan,Senanayake, Chris H.
, p. 4090 - 4093 (2014)
An efficient production synthesis of the SGLT-2 inhibitor Empagliflozin (5) from acid 1 is described. The key tactical stage involves I/Mg exchange of aryl iodide 2 followed by addition to glucono lactone 3 in THF. Subsequent in situ treatment of the resulting lactol with HCl in MeOH produces β-anomeric methyl glycopyranoside 4 which is, without isolation, directly reduced with Et3SiH mediated by AlCl3 as a Lewis acid in CH 2Cl2/MeCN to afford 5 in 50% overall yield. The process was implemented for production on a metric ton scale for commercial launch.
