16208-51-8 Usage
Description
Dimesna, also known as Mesna EP Impurity D, is a chemical compound that plays a crucial role in the pharmaceutical industry. It is a white solid with the ability to react with urotoxic metabolites, such as acrolein, produced by oxazaphosphorines like cyclophosphamide or ifosfamide. Dimesna does not possess any antitumor activity but is essential in mitigating the harmful side effects of certain cancer-fighting drugs.
Uses
Used in Pharmaceutical Industry:
Dimesna is used as a protective agent for the bladder wall, preventing the harmful effects of some cancer-fighting drugs. It reacts with urotoxic metabolites, such as acrolein, produced by oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. This helps in reducing the risk of bladder damage and other side effects associated with the use of these antineoplastic drugs. Importantly, Dimesna does not interfere with the antitumor activity of the cancer-fighting drugs, making it a valuable addition to the treatment regimen.
Check Digit Verification of cas no
The CAS Registry Mumber 16208-51-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,0 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 16208-51:
(7*1)+(6*6)+(5*2)+(4*0)+(3*8)+(2*5)+(1*1)=88
88 % 10 = 8
So 16208-51-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H10O6S4.2Na/c5-13(6,7)3-1-11-12-2-4-14(8,9)10;;/h1-4H2,(H,5,6,7)(H,8,9,10);;/q;2*+1/p-2