162148-45-0

Basic information

• Product Name: 1,4,7,10-Tetraazacyclododecane-1,7-dicarboxylic acid, bis(phenylmethyl) ester
• Synonyms: 1,7--bis(benzyloxycarbonyl)-1,4,7,10--tetraazacyclododecane;1,7-bis(benzyloxycarbonyl)- 1,4,7,10-tetraazacyclododecane;Bis(phenylmethyl) 1,4,7,10-tetraazacyclododecane-1,7-dicarboxylate;1,7-bis(benzyloxycarbonyl)-1,4,7,10-tetraazacyclododecane;N1,N3-di(benzyloxycarbonyl)cyclen;1,4,7,10-Tetraaza-cyclododecane-1,7-dicarboxylic acid dibenzyl ester;1,7-bis(benzyloxycarbonyl)-1,4-7,10-tetraazacyclododecane
• CAS NO: 162148-45-0
• Molecular Formula: C24H32N4O4
• Molecular Weight: 440.542
• Mol File: 162148-45-0.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: 1,4,7,10-Tetraazacyclododecane-1,7-dicarboxylic acid, bis(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,7,10-Tetraazacyclododecane-1,7-dicarboxylic acid, bis(phenylmethyl) ester(162148-45-0)
• EPA Substance Registry System: 1,4,7,10-Tetraazacyclododecane-1,7-dicarboxylic acid, bis(phenylmethyl) ester(162148-45-0)

Safety Data

• Hazardous Substances Data: 162148-45-0(Hazardous Substances Data)

Usage

Description

1,4,7,10-Tetraazacyclododecane-1,7-dicarboxylic acid, bis(phenylmethyl) ester, also known as Bis-CBZ-Cyclen, is a complex organic compound with a cyclic structure and ester functional groups. It is a reactive intermediate that plays a crucial role in the synthesis of high-spin iron(II) and cobalt(II) N-methylated N-methylpicolyl cyclen complexes.

Uses

Used in Chemical Synthesis:
1,4,7,10-Tetraazacyclododecane-1,7-dicarboxylic acid, bis(phenylmethyl) ester is used as a reactive intermediate for the synthesis of high-spin iron(II) and cobalt(II) N-methylated N-methylpicolyl cyclen complexes. These complexes are valuable in the field of chemistry due to their unique properties and potential applications.
Used in Analytical Chemistry:
In the field of analytical chemistry, Bis-CBZ-Cyclen is used as a paraSHIFT agent with large temperature-dependent shifts. This makes it a valuable tool for researchers and scientists working on the development of new analytical techniques and methods.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, the pharmaceutical industry could potentially benefit from the unique properties of Bis-CBZ-Cyclen. Its ability to form complexes with high-spin iron(II) and cobalt(II) ions may lead to the development of new drugs or drug delivery systems.
Used in Material Science:
The unique structure and properties of Bis-CBZ-Cyclen may also find applications in material science, particularly in the development of new materials with specific properties or functions. Researchers in this field may explore its potential for creating novel materials with applications in various industries.

Upstream product

• 10045-25-7 1,4,7,10-tetraazacyclododecane tetrahydrochloride 
• 501-53-1 benzyl chloroformate 
• 38616-66-9 cyclen 
• 294-90-6 1,4,7,10-tetraazacyclododecan 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 31139-36-3 dibenzyl dicarbonate 

Downstream Products

• 748185-88-8 1,7-bis(benzyloxycarbonyl)-4-(9-phenanthrenylmethyl)-1,4,7,10-tetraazacyclododecane 
• 1350571-66-2 C₄₀H₅₉N₅O₉ 
• 1333386-69-8 dibenzyl 4,10-bis(6-(bis(3-ethoxy-3-oxopropyl)amino)-6-oxohexyl)-1,4,7,10-tetraazacyclododecane-1,7-dicarboxylate 
• 187240-78-4 dibenzyl 4,10-bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,7-dicarboxylate 
• 1331910-03-2 1,7-bis-(carbo-tert-butoxymethyl)-4-(4'-aminobenzyl)-1,4,7,10-tetraazacyclododecane 
• 1598412-64-6 1,7-bis(benzyloxycarbonyl)-4,10-bis(2-methylphenyl acetate)tetraazacyclododecane 
• 1598412-66-8 1,7-(2-hydroxybenzyl)-1,4,7,10-tetraazacyclododecane 
• 748185-86-6 1,7-bis(benzyloxycarbonyl)-4-(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane 
• 748185-87-7 1,7-bis(benzyloxycarbonyl)-4,10-bis(6-fluoro-2-quinolinylmethyl)-1,4,7,10-tetraazacyclododecane 
• 524922-36-9 4,10-dihydroxy-1,4,7,10-tetraazacyclododecane-1,7-dicarboxylic acid dibenzyl ester 
• 357213-56-0 4-(7-Fluoro-isoquinolin-3-ylmethyl)-1,4,7,10-tetraaza-cyclododecane-1,7-dicarboxylic acid dibenzyl ester 
• 325147-65-7 1,7-di(carboxymethyl)-4,10-di(benzyloxycarbonyl)-1,4,7,10-tetraazacyclododecane 
• 182156-62-3 1,7-Dicarboxymethyl-4,10-di(benzyloxycarbonyl)-1,4,7,10-tetrazacyclododecane 
• 200951-87-7 1,7-bis(benzyloxycarbonyl)-1,4,7,10-tetraazacyclododecane-4,10-bis(methanephosphonic acid diethyl ester) 

Relevant articles and documents

Comparative in vivo behavior studies of cyclen-based copper-64 complexes: Regioselective synthesis, X-ray structure, radiochemistry, log P, and biodistribution

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