16215-12-6

Basic information

• Product Name: 4-chlorophenyl 2-phenylvinyl sulfone
• Synonyms: 4-chlorophenyl 2-phenylvinyl sulfone;1-chloro-4-{[(E)-2-phenylethenyl]sulfonyl}benzene
• CAS NO: 16215-12-6
• Molecular Formula: C₁₄H₁₁ClO₂S
• Molecular Weight: 278.75394
• Mol File: 16215-12-6.mol
• Article Data: 48

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chlorophenyl 2-phenylvinyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chlorophenyl 2-phenylvinyl sulfone(16215-12-6)
• EPA Substance Registry System: 4-chlorophenyl 2-phenylvinyl sulfone(16215-12-6)

Safety Data

• Hazardous Substances Data: 16215-12-6(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 40137-12-0 diethyl<<(p-chlorophenyl)sulfonyl>methyl>phosphonate 
• 100-42-5 styrene 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 66680-87-3 (E)-1-phenyl-(2-tributylstannyl)ethene 
• 32228-21-0 (E)-(styryl)(4-chloro-phenyl)sulfide 
• 3405-89-8 2-(4-chloro-phenylsulfonyl)acetic acid 
• 92150-69-1 1-chloro-4-((phenylethynyl)sulfonyl)benzene 
• 932-88-7 1-iodo-2-phenylethyne 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 69770-58-7 diethyl<<(p-chlorophenyl)sulfide>methyl>phosphonate 
• 3405-88-7 (4-chlorophenylthio)acetic acid 
• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 536-74-3 phenylacetylene 

Downstream Products

• 40582-90-9 p-chlorophenyl 2-phenylhexyl sulfone 
• 1097725-23-9 methyl 4-(4-chlorophenylsulfonyl)-3-phenylbutyrate 

Relevant articles and documents

Intermolecular [2 + 2] Photocycloaddition of α,β-Unsaturated Sulfones: Catalyst-Free Reaction and Catalytic Variants

2-Aryl-1-sulfonyl-substituted cyclobutanes were prepared in an intermolecular [2 + 2] photocycloaddition from various α,β-unsaturated sulfones and olefins upon irradiation at λ = 300 nm (26 examples, 60-99% yield). Lewis acids catalyzed the [2 + 2] photocycloaddition of 2-benzimidazolyl styryl sulfones. At short wavelengths, the latter substrates underwent C-S bond cleavage but AlBr3 (5 mol %) allowed for an intermolecular reaction with 2,3-dimethyl-2-butene at longer wavelengths. A chiral-at-metal Lewis acid (2 mol %) facilitated an enantioselective reaction (up to 77% ee).

Base-controlled divergent synthesis of vinyl sulfones from (benzylsulfonyl)benzenes and paraformaldehyde

A tuneable metal-free protocol for the selective preparation of a-substituted vinyl sulfone and (E)-vinyl sulfone derivatives has been described. In this process, stable paraformaldehyde was used as the carbon source. The base played an important role in the selectivity control of transformations. More than 50 products were synthesized with excellent chemoselectivity and broad functional group tolerance.