162300-67-6

Basic information

• Product Name: (R)-(4-chlorophenyl)(4'-methylphenyl)methanol
• Synonyms: (R)-(4-chlorophenyl)(4'-methylphenyl)methanol
• CAS NO: 162300-67-6
• Molecular Weight: 232.71
• Mol File: 162300-67-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (R)-(4-chlorophenyl)(4'-methylphenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(4-chlorophenyl)(4'-methylphenyl)methanol(162300-67-6)
• EPA Substance Registry System: (R)-(4-chlorophenyl)(4'-methylphenyl)methanol(162300-67-6)

Safety Data

• Hazardous Substances Data: 162300-67-6(Hazardous Substances Data)

Upstream product

• 5084-80-0 tri(4-tolyl)boroxine 
• 104-88-1 4-chlorobenzaldehyde 
• 7519-91-7 tris(4-chlorophenyl)boroxine 
• 104-87-0 4-methyl-benzaldehyde 
• 5720-05-8 4-methylphenylboronic acid 
• 1679-18-1 4-Chlorophenylboronic acid 
• 1352313-28-0 C₈H₁₀Zn 

Relevant articles and documents

Diastereomeric aziridine carbinol catalyzed enantioselective arylation reaction: Toward the asymmetric synthesis of both enantiomers of chiral 3-aryl phthalide

The diastereomeric aziridine carbinols are applied, respectively, as efficient chiral ligand in the catalysis of asymmetric arylation and sequential arylation-lactonization cascade. The two diastereomers, which are facilely synthesized from the same chiral source, function as pseudo enantiomers in arylation of aromatic aldehydes providing the different enantiomers of the diarylmethanols with almost the same excellent enantioselectivities. The arylation method is also carried out in tandem with lactonization process to afford a concise synthetic approach to both enantiomers of optically active 3-aryl phthalide.

Chirality control in the enantioselective arylation of aromatic aldehydes catalyzed by cis-(1R,2S)-2-benzamidocyclohexanecarboxylic acid derived 1,3-aminoalcohols

A series of chiral 1,3-aminoalcohols derived from cis-(1R,2S)-2-benzamidocyclohexanecarboxylic acid were synthesized and applied to the enantioselective arylation of aromatic aldehydes. The reactions exhibited good yields (up to 90%) and moderate to high

Novel axially chiral phosphine ligand with a fluoro alcohol moiety for Rh-catalyzed asymmetric arylation of aromatic aldehydes

A new chiral phosphine ligand (R)-1 possessing a fluoroalcohol moiety was prepared. The (R)-1-coordinated Rh(I) complex showed an excellent catalytic activity for asymmetric 1,2-addition of arylboronic acids to aldehydes to afford highly enantioenriched diarylmethanols. The fluoroalcohol moiety in ligand (R)-1 plays a pivotal role for the high enantioselectivity of the present Rh(I)-catalyzed transformation.