162375-32-8

Basic information

• Product Name: N-2'-propenyl-Z-3-chloro-2-(phenylthio)propenamide
• Synonyms: N-2'-propenyl-Z-3-chloro-2-(phenylthio)propenamide
• CAS NO: 162375-32-8
• Molecular Weight: 253.752
• Mol File: 162375-32-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-2'-propenyl-Z-3-chloro-2-(phenylthio)propenamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-2'-propenyl-Z-3-chloro-2-(phenylthio)propenamide(162375-32-8)
• EPA Substance Registry System: N-2'-propenyl-Z-3-chloro-2-(phenylthio)propenamide(162375-32-8)

Safety Data

• Hazardous Substances Data: 162375-32-8(Hazardous Substances Data)

Upstream product

• 162375-40-8 N-2'-propenyl-2-(phenylthio)propanamide 
• 106593-37-7 N-2'-propenyl-2-chloropropanamide 
• 108-98-5 thiophenol 
• 930-69-8 sodium thiophenolate 

Downstream Products

• 1294897-70-3 C₁₇H₂₃NO₃S 
• 1294896-90-4 (Z)-N-(2-propenyl)-2-(phenylthio)-2-butenamide 
• 1294897-69-0 C₁₆H₂₁NO₃S 
• 1294897-45-2 (Z)-N-(2-propenyl)-3-methoxy-2-(phenylthio)propenamide 
• 1043925-56-9 N-2'-propenyl-Z-3-chloro-2-(benzenesulfinyl)propenamide 

Relevant articles and documents

Investigation of the synthetic and mechanistic aspects of the highly stereoselective transformation of α-thioamides to α-thio-β- chloroacrylamides

Treatment of a series of α-thioamides with N-chlorosuccinimide results in efficient transformation to the analogous α-thio-β- chloroacrylamides. The mechanistic pathway has been established through isolation and characterisation of intermediate compounds. The scope of the transformation has been explored - aryl and alkylthio substituents, primary, secondary and tertiary amides can be employed. In most instances, the chloroacrylamides are formed exclusively as the Z-stereoisomer; however, with tertiary propanamides or with amides derived from butanoic or pentanoic acid a mixture of E- and Z-stereoisomers is formed. The Royal Society of Chemistry.