1623791-99-0 Usage
Description
Azido-PEG8-t-butyl ester is a click chemistry compound consisting of an azide group and a t-butyl ester moiety. The hydrophilic PEG (polyethylene glycol) spacer increases solubility in aqueous media, making it suitable for various applications. The azide group can react with alkyne, BCN, DBCO, and other click chemistry-compatible molecules to form a stable triazole linkage, which is useful for creating covalent bonds in biological systems.
Uses
Used in Bioconjugation:
Azido-PEG8-t-butyl ester is used as a bioconjugation agent for the covalent attachment of biomolecules, such as proteins, peptides, and nucleic acids, to other molecules or surfaces. The stable triazole linkage formed through click chemistry ensures the strong and specific binding of the biomolecule to its target.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Azido-PEG8-t-butyl ester is used as a component in drug delivery systems. The hydrophilic PEG spacer enhances the solubility and bioavailability of the drug, while the azide group allows for the covalent attachment of the drug molecule to a carrier or targeting moiety through click chemistry, improving the drug's efficacy and reducing side effects.
Used in Materials Science:
In materials science, Azido-PEG8-t-butyl ester is used as a building block for the development of functional materials with tailored properties. The azide group can be used to create crosslinked networks or to attach specific functional groups to a material, enabling the design of materials with applications in areas such as sensors, coatings, and adhesives.
Used in Chemical Synthesis:
Azido-PEG8-t-butyl ester is used as an intermediate in the synthesis of various chemical compounds, particularly those involving click chemistry. The azide group provides a versatile handle for further functionalization and modification of the molecule, allowing for the creation of a wide range of products with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1623791-99-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,3,7,9 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1623791-99:
(9*1)+(8*6)+(7*2)+(6*3)+(5*7)+(4*9)+(3*1)+(2*9)+(1*9)=190
190 % 10 = 0
So 1623791-99-0 is a valid CAS Registry Number.
1623791-99-0Relevant articles and documents
DIRECTED CONJUGATION TECHNOLOGIES
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Paragraph 0579; 0580, (2021/05/29)
Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, provided technologies are useful for preparing antibody conjugates.
