162401-69-6

Basic information

• Product Name: Benzoic acid, 4-(cyclopropylMethoxy)-3-(difluoroMethoxy)-
• Synonyms: Benzoic acid, 4-(cyclopropylMethoxy)-3-(difluoroMethoxy)-;Roflumilast impurity 15
• CAS NO: 162401-69-6
• Molecular Formula: C₁₂H₁₂F₂O₄
• Molecular Weight: 258.2180864
• Mol File: 162401-69-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 4-(cyclopropylMethoxy)-3-(difluoroMethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(cyclopropylMethoxy)-3-(difluoroMethoxy)-(162401-69-6)
• EPA Substance Registry System: Benzoic acid, 4-(cyclopropylMethoxy)-3-(difluoroMethoxy)-(162401-69-6)

Safety Data

• Hazardous Substances Data: 162401-69-6(Hazardous Substances Data)

Downstream Products

• 162401-32-3 roflumilast 

Relevant articles and documents

FLUOROALKOXY-SUBSTITUTED BENZAMIDES AND THEIR USE AS CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS

Compounds of formula (I), in which one of the substituents R1 or R2 stands for hydrogen, 1-6C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy, benzyloxy or totally or partially fluorine-substituted 1-4C-alkoxy, and the other stands for totally or partially fluorine-substituted 1-4C-alkoxy, and R3 stands for phenyl, pyridyl, R31, R32 and R33-substituted phenyl or R34, R35, R36 and R37-substituted pyridyl, in which R31 stands for hydroxy, halogen, cyano, carboxyl, trifluoromethyl 1-4C-alkyl, 1-4C-alkoxy, 1-4C-alkoxycarbonyl, 1-4C-alkylcarbonyl, 1-4C-alkylcarbonyloxy, amino, mono- or di-1-4C-atkylamino or 1-4C-alkylcarbonylamino; R32 stands for hydrogen, hydroxy, halogen, amino, trifluoromethyl, 1-4C-alkyl or 1-4C-alkoxy; R33 stands for hydrogen, halogen, 1-4C-alkyl or 1-4C-alkoxy; R34 stands for hydroxy, halogen, cyano, carboxyl, 1-4C-alkyl, 1-4C-alkoxy, 1-4C-alkoxycarbonyl or amino; R35 stands for hydrogen, halogen, amino or 1-4C-alkyl; R36 stands for hydrogen or halogen; and R37 stands for hydrogen or halogen. These compounds constitute new effective bronchotherapeutic drugs