1625-11-2 Usage
Description
6α-Methyl Hydrocortisone 21-Acetate, also known as Methylprednisolone acetate (M326035) USP impurity, is a white to off-white solid with specific chemical properties. It is a synthetic glucocorticoid derived from hydrocortisone, which is a naturally occurring hormone in the adrenal cortex. 6α-Methyl Hydrocortisone 21-Acetate exhibits potent anti-inflammatory and immunosuppressive activities, making it a valuable pharmaceutical agent for various medical applications.
Uses
Used in Pharmaceutical Industry:
6α-Methyl Hydrocortisone 21-Acetate is used as an active pharmaceutical ingredient (API) for the development of medications targeting inflammation and immune system disorders. Its potent anti-inflammatory and immunosuppressive properties make it effective in treating conditions such as rheumatoid arthritis, lupus, asthma, and various skin diseases.
Used in Steroid Hormone Replacement Therapy:
In the field of endocrinology, 6α-Methyl Hydrocortisone 21-Acetate is used as a steroid hormone replacement therapy for patients with adrenal insufficiency or other conditions requiring glucocorticoid supplementation. It helps to maintain normal physiological functions and alleviate symptoms associated with hormone deficiency.
Used in Veterinary Medicine:
6α-Methyl Hydrocortisone 21-Acetate is also utilized in veterinary medicine as an anti-inflammatory and immunosuppressive agent for the treatment of various conditions in animals, such as allergies, skin diseases, and inflammatory bowel disease.
Used in Research and Development:
As a USP impurity, 6α-Methyl Hydrocortisone 21-Acetate is employed in the research and development of new drugs and therapies. It serves as a reference compound for quality control, stability testing, and method development in the pharmaceutical industry, ensuring the safety and efficacy of medications containing glucocorticoids.
Check Digit Verification of cas no
The CAS Registry Mumber 1625-11-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,2 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1625-11:
(6*1)+(5*6)+(4*2)+(3*5)+(2*1)+(1*1)=62
62 % 10 = 2
So 1625-11-2 is a valid CAS Registry Number.
InChI:InChI=1/C24H34O6/c1-13-9-16-17-6-8-24(29,20(28)12-30-14(2)25)23(17,4)11-19(27)21(16)22(3)7-5-15(26)10-18(13)22/h10,13,16-17,19,21,27,29H,5-9,11-12H2,1-4H3/t13-,16-,17-,19-,21+,22-,23-,24-/m0/s1
1625-11-2Relevant articles and documents
Burn et al.
, p. 1155,1157 (1969)
9α-dehalogenation process
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, (2008/06/13)
The present invention involves improved processes for the dehalogenation of 9α-halosteroids (I) STR1 to produce the corresponding 11β-hydroxy steroids (II) STR2 which are known to be useful as pharmaceutical, where the improvements comprise (1) adding the 9α-halo steroid (I) to the chromium and (2) using catalytic amounts of chromium in the presence of a means of converting chromium (II) to chromium (III).
