1626-36-4

Basic information

• Product Name: 1H-Benzimidazole, 5-methyl-2-(phenoxymethyl)-
• CAS NO: 1626-36-4
• Molecular Formula: C15H14N2O
• Molecular Weight: 238.289
• Mol File: 1626-36-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Benzimidazole, 5-methyl-2-(phenoxymethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole, 5-methyl-2-(phenoxymethyl)-(1626-36-4)
• EPA Substance Registry System: 1H-Benzimidazole, 5-methyl-2-(phenoxymethyl)-(1626-36-4)

Safety Data

• Hazardous Substances Data: 1626-36-4(Hazardous Substances Data)

Usage

Structure

A chemical compound with a benzimidazole ring, a methyl group, and a phenoxymethyl group attached to the nitrogen atom

Usage

Commonly used in pharmaceutical research as a building block for the synthesis of various pharmaceutical drugs and compounds

Usage

Used as a reagent in organic synthesis

Usage

Serves as a starting material for the preparation of biologically active molecules

Importance

A versatile and important compound with various potential applications in the field of chemistry and pharmaceuticals

Upstream product

• 496-72-0 4-methyl-1,2-diaminobenzene 
• 122-59-8 2-phenoxyacetic acid 

Relevant articles and documents

Synthesis and structure-activity relationships of new antimicrobial active multisubstituted benzazole derivatives

A series of multisubstituted benzoxazoles, benzimidazoles, and benzothiazoles (5-7) as non-nucleoside fused isosteric heterocyclic compounds was synthesized and tested for their antibacterial activities against various Gram-positive and Gram-negative bacteria and antifungal activity against the fungus Candida albicans. Microbiological results indicated that the synthesized compounds possessed a broad spectrum of activity against the tested microorganisms at MIC values between 100 and 3.12 μg/ml. Structure-activity relationships (SAR) studies revealed that benzothiazole ring system enhanced the antimicrobial activity against Staphylococcus aureus. In these sets of non-nucleoside fused heterocyclic compounds electron withdrawing groups at position 5 of the benzazoles increased the activity against C. albicans.

Synthesis and microbiological activity of 5(or 6)-methyl-2-substituted benzoxazole and benzimidazole derivatives

The synthesis and microbiological activity of a new series of 5(or 6)- methyl-2-substituted benzoxazoles (IVa-n) and benzimidazoles (Va-h) were described. The in vitro microbiological activity of the compounds was determined against gram-positive, gram-ne