162607-20-7 Usage
Description
5-Methylthiophene-2-boronic acid is an organic compound with the chemical formula C5H7BS. It is a white to light yellow powder and is commonly used as a reactant in Suzuki-Miyaura cross-coupling reactions, a type of carbon-carbon bond-forming reaction in organic chemistry.
Uses
Used in Pharmaceutical Industry:
5-Methylthiophene-2-boronic acid is used as a reactant for Suzuki-Miyaura cross-coupling reactions, which are crucial in the synthesis of various pharmaceutical compounds. These reactions allow for the formation of complex molecular structures with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 5-Methylthiophene-2-boronic acid serves as a valuable reactant for Suzuki-Miyaura cross-coupling reactions. This enables the creation of a wide range of organic compounds with diverse properties and potential applications in various industries, including materials science, agrochemicals, and specialty chemicals.
Used in Research and Development:
5-Methylthiophene-2-boronic acid is also utilized in research and development settings, where it aids in the exploration of new chemical reactions and the development of novel synthetic pathways. Its use in Suzuki-Miyaura cross-coupling reactions contributes to the advancement of organic chemistry and the discovery of new compounds with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 162607-20-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,6,0 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 162607-20:
(8*1)+(7*6)+(6*2)+(5*6)+(4*0)+(3*7)+(2*2)+(1*0)=117
117 % 10 = 7
So 162607-20-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H7BO2S/c1-4-2-3-5(9-4)6(7)8/h2-3,7-8H,1H3
162607-20-7Relevant articles and documents
A C-H borylation approach to suzuki-miyaura coupling of typically unstable 2-heteroaryl and polyfluorophenyl boronates
Robbins, Daniel W.,Hartwig, John F.
supporting information; experimental part, p. 4266 - 4269 (2012/10/08)
A method for the synthesis of biaryls and heterobiaryls from arenes and haloarenes without the intermediacy of unstable boronic acids is described. Pinacol boronate esters that are analogous to unstable boronic acids are formed in high yield by iridium-catalyzed C-H borylation of heteroarenes and fluoroarenes. These boronates are stable in the solid state or in solution and can be generated and used in situ. They couple with aryl halides in the presence of simple palladium catalysts, providing a convenient route to biaryl and heteroaryl products that have been challenging to prepare via boronic acids.
